ASPECTOS RELEVANTES DE LEISHMANIAVIRUS EN AISLADOS DE Leishmania spp.

Armando Assair Bonilla Fong

Enviado enero 24, 2023

Publicado 2023-01-25

Artículos

Vol. 33 Núm. 1 (2023): Scientia

ASPECTOS RELEVANTES DE LEISHMANIAVIRUS EN AISLADOS DE Leishmania spp.

Armando Assair Bonilla Fong⁺⁻

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Publicado: 2023-01-25

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Bonilla Fong, A. A. (2023). ASPECTOS RELEVANTES DE LEISHMANIAVIRUS EN AISLADOS DE Leishmania spp. Scientia, 33(1), 85–96. Recuperado a partir de https://revistas.up.ac.pa/index.php/scientia/article/view/3534

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0.

Resumen

La leishmaniasis es una enfermedad vectorial causada por protozoarios del género Leishmania que afecta a células macrofágicas del hospedero. Las complicaciones clínicas y fallas en el tratamiento se han relacionado con la presencia de un virus de ácido ribonucleico de doble cadena de la familia Totiviridae. En el nuevo mundo se encuentra exclusivamente el virus de Leishmania 1 y en el viejo mundo, el virus de Leishmania 2. Se conoce que el virus interactúa con el receptor tipo Toll 3 en las células del hospedador para estimular la producción de citoquinas proinflamatorias que resulta en la gravedad de la enfermedad y la supervivencia del parásito. Esta revisión corta explora lo observado y estudiado sobre el leishmaniavirus desde la perspectiva histórica e inmunológica.

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Atayde, V. D., da Silva Lira Filho, A., Chaparro, V., Zimmermann, A., Martel, C., Jaramillo, M., & Olivier, M. (2019). Exploitation of the Leishmania exosomal pathway by Leishmania RNA virus 1. Nature Microbiology, 4(4), 714–723. https://doi.org/10.1038/s41564-018-0352-y
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Parra-Muñoz, M., Aponte, S., Ovalle-Bracho, C., Saavedra, C. H., & Echeverry, M. C. (2021). detection of leishmania RNA virus in clinical samples from cutaneous leishmaniasis patients varies according to the type of sample. American Journal of Tropical Medicine and Hygiene, 104(1), 233–239. https://doi.org/10.4269/AJTMH.20-0073
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[1] Adaui, V., Lye, L. F., Akopyants, N. S., Zimic, M., Llanos-Cuentas, A., Garcia, L., Maes, I., de Doncker, S., Dobson, D. E., Arevalo, J., Dujardin, J. C., & Beverley, S. M. (2016). Association of the endobiont double-stranded RNA virus LRV1 with treatment failure for human leishmaniasis caused by leishmania braziliensis in Peru and Bolivia. Journal of Infectious Diseases, 213(1), 112–121. https://doi.org/10.1093/infdis/jiv354

[2] Atayde, V. D., da Silva Lira Filho, A., Chaparro, V., Zimmermann, A., Martel, C., Jaramillo, M., & Olivier, M. (2019). Exploitation of the Leishmania exosomal pathway by Leishmania RNA virus 1. Nature Microbiology, 4(4), 714–723. https://doi.org/10.1038/s41564-018-0352-y

[3] Barrett, M. P., & Croft, S. L. (2012). Management of trypanosomiasis and leishmaniasis. In British Medical Bulletin (Vol. 104, Issue 1, pp. 175–196). https://doi.org/10.1093/bmb/lds031

[4] Brettmann, E. A., Shaik, J. S., Zangger, H., Lye, L. F., Kuhlmann, F. M., Akopyants, N. S., Oschwald, D. M., Owens, K. L., Hickerson, S. M., Ronet, C., Fasel, N., & Beverley, S. M. (2016). Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response. Proceedings of the National Academy of Sciences of the United States of America, 113(43), 11998–12005. https://doi.org/10.1073/pnas.1615085113

[5] Cai, G., Myers, K., Hillman, B. I., & Fry, W. E. (2009). A novel virus of the late blight pathogen, Phytophthora infestans, with two RNA segments and a supergroup 1 RNA-dependent RNA polymerase. Virology, 392(1), 52–61. https://doi.org/10.1016/j.virol.2009.06.040

[6] Cantanhêde, L. M., da Silva Júnior, C. F., Ito, M. M., Felipin, K. P., Nicolete, R., Salcedo, J. M. V., Porrozzi, R., Cupolillo, E., & Ferreira, R. de G. M. (2015). Further Evidence of an Association between the Presence of Leishmania RNA Virus 1 and the Mucosal Manifestations in Tegumentary Leishmaniasis Patients. PLoS Neglected Tropical Diseases, 9(9). https://doi.org/10.1371/journal.pntd.0004079

[7] Chahar, H. S., Bao, X., & Casola, A. (2015). Exosomes and their role in the life cycle and pathogenesis of RNA viruses. In Viruses (Vol. 7, Issue 6, pp. 3204–3225). MDPI AG. https://doi.org/10.3390/v7062770

[8] de Oliveira Ramos Pereira, L., Maretti-Mira, A. C., Rodrigues, K. M., Lima, R. B., de Oliveira-Neto, M. P., Cupolillo, E., Pirmez, C., & de Oliveira, M. P. (2013). Severity of tegumentary leishmaniasis is not exclusively associated with Leishmania RNA virus 1 infection in Brazil. Memorias Do Instituto Oswaldo Cruz, 108(5), 665–667. https://doi.org/10.1590/0074-0276108052013021

[9] de Souza, M. M., Manzine, L. R., da Silva, M. V. G., Bettini, J., Portugal, R. V., Cruz, A. K., Arruda, E., & Thiemann, O. H. (2014). An improved purification procedure for Leishmania RNA virus (LRV). In Brazilian Journal of Microbiology (Vol. 45, Issue 2). https://doi.org/10.1590/S1517-83822014000200044

[10] Dreux, M., Garaigorta, U., Boyd, B., Décembre, E., Chung, J., Whitten-Bauer, C., Wieland, S., & Chisari, F. v. (2012). Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity. Cell Host and Microbe, 12(4), 558–570. https://doi.org/10.1016/j.chom.2012.08.010

[11] Eren, R. O., Reverte, M., Rossi, M., Hartley, M. A., Castiglioni, P., Prevel, F., Martin, R., Desponds, C., Lye, L. F., Drexler, S. K., Reith, W., Beverley, S. M., Ronet, C., & Fasel, N. (2016). Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence. Cell Host and Microbe, 20(3), 318–328. https://doi.org/10.1016/j.chom.2016.08.001

[12] Forterre, P. (2010). Defining Life: The Virus Viewpoint. Origins of Life and Evolution of Biospheres, 40(2), 151–160. https://doi.org/10.1007/s11084-010-9194-1

[13] Grybchuk, D., Akopyants, N. S., Kostygov, A. Y., Konovalovas, A., Lye, L. F., Dobson, D. E., Zangger, H., Fasel, N., Butenko, A., Frolov, A. O., Votýpka, J., D’Avila-Levy, C. M., Kulich, P., Moravcová, J., Plevka, P., Rogozin, I. B., Serva, S., Lukeš, J., Beverley, S. M., & Yurchenko, V. (2018). Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania. Proceedings of the National Academy of Sciences of the United States of America, 115(3), E506–E515. https://doi.org/10.1073/pnas.1717806115

[14] Guilbride, L., Myler, P. J., & Stuart, K. (1992). Distribution and sequence divergence of LRV1 viruses among different Leishmania species. In Molecular and Biochemical Parasitology (Vol. 54, Issue 1). https://doi.org/10.1016/0166-6851(92)90099-6

[15] Hartley, M. A., Drexler, S., Ronet, C., Beverley, S. M., & Fasel, N. (2014). The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis. In Trends in Parasitology (Vol. 30, Issue 8, pp. 412–422). Elsevier Ltd. https://doi.org/10.1016/j.pt.2014.05.006

[16] Ives, A., Ronet, C., Prevel, F., Ruzzante, G., Fuertes-Marraco, S., Schutz, F., Zangger, H., Revaz-Breton, M., Lye, L. F., Hickerson, S. M., Beverley, S. M., Acha-Orbea, H., Launois, P., Fasel, N., & Masina, S. (2011). Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis. Science, 331(6018), 775–778. https://doi.org/10.1126/science.1199326

[17] Kariyawasam, R., Grewal, J., Lau, R., Purssell, A., Valencia, B. M., Llanos-Cuentas, A., & Boggild, A. K. (2017). Influence of Leishmania RNA Virus 1 on Proinflammatory Biomarker Expression in a Human Macrophage Model of American Tegumentary Leishmaniasis. Journal of Infectious Diseases, 216(7), 877–886. https://doi.org/10.1093/infdis/jix416

[18] Kariyawasam, R., Lau, R., Valencia, B. M., Llanos-Cuentas, A., & Boggild, A. K. (2020). Leishmania RNA Virus 1 (LRV-1) in leishmania (viannia) braziliensis isolates from Peru: A description of demographic and clinical correlates. American Journal of Tropical Medicine and Hygiene, 102(2), 280–285. https://doi.org/10.4269/ajtmh.19-0147

[19] Kariyawasam, R., Mukkala, A. N., Lau, R., Valencia, B. M., Llanos-Cuentas, A., & Boggild, A. K. (2019). Virulence factor RNA transcript expression in the Leishmania Viannia subgenus: Influence of species, isolate source, and Leishmania RNA virus-1. Tropical Medicine and Health, 47(1). https://doi.org/10.1186/s41182-019-0153-x

[20] Maga, J. A., Widmer, G., & LeBowitz, J. H. (1995). Leishmania RNA virus 1-mediated cap-independent translation. In Molecular and Cellular Biology (Vol. 15, Issue 9). https://doi.org/10.1128/mcb.15.9.4884

[21] Mertens, P. (2004). The dsRNA viruses. Virus Research, 101(1), 3–13. https://doi.org/10.1016/j.virusres.2003.12.002

[22] Miller, J. H., & Swartzwelder, J. C. (1960). Virus-like Particles in an Entamoeba histolytica Trophozoite. In The Journal of Parasitology (Vol. 46, Issue 4). https://doi.org/10.2307/3275152

[23] Mokni, M. (2019). Cutaneous leishmaniasis. In Annales de Dermatologie et de Venereologie (Vol. 146, Issue 3, pp. 232–246). Elsevier Masson SAS. https://doi.org/10.1016/j.annder.2019.02.002

[24] Néris, P. L. N., Caldas, J. P. A., Rodrigues, Y. K. S., Amorim, F. M., Leite, J. A., Rodrigues-Mascarenhas, S., Barbosa-Filho, J. M., Rodrigues, L. C., & Oliveira, M. R. (2013). Neolignan Licarin A presents effect against Leishmania (Leishmania) major associated with immunomodulation in vitro. Experimental Parasitology, 135(2), 307–313. https://doi.org/10.1016/j.exppara.2013.07.007

[25] Olivier, M., & Zamboni, D. S. (2020). Leishmania Viannia guyanensis, LRV1 virus and extracellular vesicles: a dangerous trio influencing the faith of immune response during muco-cutaneous leishmaniasis. In Current Opinion in Immunology (Vol. 66, pp. 108–113). Elsevier Ltd. https://doi.org/10.1016/j.coi.2020.08.004

[26] Parra-Muñoz, M., Aponte, S., Ovalle-Bracho, C., Saavedra, C. H., & Echeverry, M. C. (2021). detection of leishmania RNA virus in clinical samples from cutaneous leishmaniasis patients varies according to the type of sample. American Journal of Tropical Medicine and Hygiene, 104(1), 233–239. https://doi.org/10.4269/AJTMH.20-0073

[27] Reithinger, R., Dujardin, J. C., Louzir, H., Pirmez, C., Alexander, B., & Brooker, S. (2007). Cutaneous leishmaniasis. In Lancet Infectious Diseases (Vol. 7, Issue 9, pp. 581–596). https://doi.org/10.1016/S1473-3099(07)70209-8

[28] Saberi, R., Fakhar, M., Mohebali, M., Anvari, D., & Gholami, S. (2019). Global status of synchronizing Leishmania RNA virus in Leishmania parasites: A systematic review with meta-analysis. In Transboundary and Emerging Diseases (Vol. 66, Issue 6, pp. 2244–2251). Blackwell Publishing Ltd. https://doi.org/10.1111/tbed.13316

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