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Panama has a geographical position that serves the global purpose as a platform for maritime, commercial, real estate, financial services and free zones, where the banking industry serves as a catalyst for all these processes. The object of study is evaluating the management of capital and transactions have caused the country to be subject to investigations and obliged to comply with a series of international standards, in many cases not applicable to other countries where these movements They are developed without the respective controls. To address the research and with the objective of summarizing the regulatory process around money laundering in Panama, a non-experimental and qualitative research is presented, with a descriptive scope of the period between the years 2013 to 2021. Documentary analysis techniques and collected information that expose the development of laws and decrees that have been issued to regulate money laundering and money laundering in the country are also provided for a better understanding of the study.