This paper explained what the crime of Unlawful Appropriation is in the criminal legal system of the Republic of Panama. It started with an analysis of the Panamanian criminal theory, as well as a hermeneutical study of the Penal Code about its different modalities (exegetical interpretation method). An explanation of the characteristics that make up this crime was carried out. Two criminal cases of the Panamanian Administration of Justice related to Unlawful Appropriation were also studied. For this, techniques were used to review Panamanian legal sources, jurisprudence analysis and theory review -mainly Panamanian-. In it, it was concluded, among others, that the crime of Unlawful Appropriation consists of the intention of the person to be the owner of an asset without the mediation of a legal and legitimate relationship that allows it, since that asset belongs to another person.