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The article explores the experiences and perceptions of patients with non-communicable chronic diseases and healthcare professionals in Mexico regarding the disappearance of Seguro Popular and the implementation of IMSS Bienestar. Through semi-structured interviews conducted with patients and healthcare professionals from different states in Mexico, the exploratory study reveals challenges and changes in access to health services, quality of care, and the impact of health policies. Patients reported difficulties such as the lack of medications and medical services, while healthcare professionals expressed concerns about uncertainty and resource shortages during the transition. The study highlights the need to improve communication and information about health services, as well as to address inequities in access to medical care. These findings underscore the importance of considering the perspectives of both patients and healthcare providers to achieve effective implementation of health system reforms.