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Climate change imposes serious water challenges on Panama, including droughts, floods and sea level rise. This study explores strategies to improve resilience in the La Villa river basin, taking as a reference the Dutch experience in water management. Through a bibliographic and comparative analysis, innovative and sustainable solutions that harmonize water management with the natural environment are identified. Strategies such as rainwater harvesting, groundwater recharge and water conservation in various sectors are highlighted. The study highlights the importance of a holistic and integrated approach, involving communities, authorities, and stakeholders. The findings provide valuable information for the sustainable management of water resources in Panama, particularly in the La Villa river basin, contributing to the development of policies and strategies to ensure water availability for present and future generations.