Burnout syndrome, also known in academic circles as professional Burnout syndrome, is related to sustained stress over long periods of time due to work, while digital competence is a set of knowledge, skills, attitudes, strategies, values, and awareness required when using ICT and digital media to perform teaching tasks. That is why we conducted a quantitative, cross-sectional correlational study with the aim of quantifying the prevalence of Burnout syndrome and determining whether there is a relationship between digital competencies and Burnout syndrome. The sample consisted of 50 teachers, 25 from the Faculty of Psychology and 25 from the Faculty of Pharmacy. The results show that the prevalence of Burnout syndrome is approximately 30%, while around 70% of the sample demonstrated a medium to high level of digital competency. The relationship between both variables determined by the Pearson coefficient r= -.475 was significant in emotional exhaustion, r= -.51 significant in the depersonalization scale, and r= .353 significant in the personal accomplishment scale. The results lead us to the conclusion that there is a relationship between digital competence and Burnout syndrome.