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ABSTRACT: Multiple myeloma is a malignant proliferation of plasma cells that derive from a single clone. The tumor, its products, and the host's response can cause diverse organic functional disorders and symptoms such as bone pain, fractures, renal insufficiency, predisposition to infections, anemia, hypercalcemia, and sometimes coagulation disorders, neurological symptoms, and manifestations of blood hyperviscosity.
A case of a 72-year-old male patient who experienced paresthesia that progressed to paralysis of inferior limbs is presented. During hospitalization, he presented hypercalcemia, osteolytic injuries, and acute renal insufficiency. This evidence, along with the bone marrow aspiration that revealed 68% of plasma cells, points to multiple myeloma of IgA type. Afterwards, a bibliographic review and a deep discussion of the case are presented.