Cushing's syndrome is a set of symptoms caused by Ihe excess of circulating glucocorticoids . It is an ample term , because it includes patients with different physiopathologies, but with a same phenotype. Few diseases exist where the appearance of the patient and the characteristics of physical examination are so uselul to suspect the diagnosis. We present the case of a female patient, 35 years old , wilthout pathological antecedents of importance, who displayed a clinical picture of approximalely 1 year of evolution, presenting multiple alterations in its corporal image and mood. As we studied, and correlated her clinical hislory, the physical examination and biochemical, metabolic and hormonal alteratlons, wilh imagenology, we arrived al Ihe diagnosis of Cushing's syndrome secondary to a functioning adrenal mass. Treatment was laparoscopic adrenalectomy.
Downloads
Download data is not yet available.
References
Orth DN. Medical Progress: Cushing's syndrome. N Engl J Med. 1995; 332:791-803.
Joe E. Cushing syndrome secondary to topical glucocorticoids. Dermatology Online Journal. 9(4):16.
Raff H, Findling J. A Physiologic Approach to Diagnosis of the Cushing Syndrome. Ann Intern Med. 2003; 118:980-91.
Digital Urology Journal: www.duj.com; Darracot Vaughan Jr., Surgery of the Adrenals.
Miyamori I. Clinical aspect of adrenal incidentaloma. Nippon Rinsho. 2004; 62(5):925-8.
Magiakou MA, Mastorakos G, Oldfield EH, Gomez MT, Doppman JL, Cutler GB, et al. Cushing's Syndrome in Children and Adolescents: Presentation, Diagnosis, and Therapy. N Engl J Med. 1994; 331:629-36.
Boscaro M, Barzon L, Fallo F, Sonino N. Cushing's syndrome. Lancet. 2001; 357:783-91.
Ross NS, Aron D. Hormonal evaluation of the patient with an incidentally discovered adrenal mass. N Engl J Med. 1990; 323:1401-5.
Oldfield EH, Doppman JL, Nieman LK, Chrousos GP, Miller DL, Katz DA, Cutler GB, Loriaux DL. Petrosal sinus sampling with and without corticotropin-releasing hormone for the differential diagnosis of Cushing's syndrome. N Engl J Med. 1991; 325:897-905.
Miller JW, Crapo L. The medical treatment of Cushing's syndrome. Endocr Rev. 1993; 14:443-58.
Utiger R. Treatment, and Retreatment, of Cushing's Disease. N Engl J Med. 1997; 336:215-7.