TUMOR ABDOMINAL DE APARICIÓN SÚBITA EN VARÓN DE  DOS AÑOS DE EDAD

Emmy Arrue; Juan Raúl Brin

Submitted October 20, 2024

Published 2026-04-06

Artículos de Investigación

Vol. 18 No. 2 (2005): Revista Médico Científica

SUDDEN APPEARANCE OF AN ABDOMINAL TUMOR IN A TWO-YEAR-OLD MALE

Emmy Arrue⁺⁻
Juan Raúl Brin⁺⁻

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DOI: ND

Published: 2026-04-06

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Abstract

Neuroblastoma is the most common childhood intra -abdominal malignancy and the most frequent childhood extracranial solid tumor. It is a poorly differentiated neoplasia derived from neural crest cells that typically occurs in infants and young children.

We are presenting a case study of a two-years and 8-months-old male patient who is admilted for anemia, with a previous history of claudication on walking, with pain in the left hip and weight loss since a previous month. During his hospital stay, it became palpable an abdominal mass consistent with splenomegaly which had not been apparent on initial evaluation. An abdominal ultrasonogram was performed; it revealed a solid, heterogeneous, moderately vascularized large mass.After a biopsy and relevant studies, the diagnosis of stage IV neuroblastoma with abdominal rnass. metastasis to scalp and bone marrow was made.

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References

Wood M, Abinun M, Foster H. Pyrexia of unknown origin. Arch Dis Child Ed Pract. 2004;89:63-9.
Lee YH, Lee HD, Lee YA, Lee YS, Jung JA, Hwang GG et al. Ganglioneuroblastoma presenting as dilated cardiomyopathy. Arch Dis Child. 2003;88:162-4.
Parker L, Craft AW, Brennan BMD, Eden OB. Preclinical diagnosis of abdominal tumours by ultrasound examination. Arch Dis Child. 1998;79:379.
Woods WG, Tuchman M, Robison LL, Bernstein M, Leclerc JM, Brisson LC, et al. A population-based study of the usefulness of screening for neuroblastoma. Lancet. 1996;348:1682-7.
Castleberry RP. Biology and treatment of neuroblastoma. Pediatr Clin North Am. 1997;44:919-37.
Maris JM. The biologic basis for neuroblastoma heterogeneity and risk stratification. Curr Opin Pediatr. 2005;17:7-13.
Ater JL. Neuroblastoma. En: Behrman RE, Kliegman RM, Jenson HB, editores. Tratado de pediatría de Nelson. 17ma ed. Madrid: Elsevier España; 2004. p. 1709-11.
Ferris i Tortajada J, Ortega Garcia JA, Garcia i Castell J, Lopez Andreu JA, Crehuá Gaudiza E. Risk factors for neuroblastoma. An Pediatr (Barc). 2005;63:50-60.
Schofield D, Cotran RS. Enfermedades durante la lactancia y la niñez. En: Cotran RS, Kumar V, Collins T, editores. Patología estructural y funcional. 6ta ed. México: McGraw-Hill Interamericana; 2000. p. 512-5.
National Cancer Institute. Neuroblastoma PDQ®: Treatment [monografía en Internet]. U.S. National Institutes of Health [actualizado 22 jul 2005; citado 19 sept 2005]. Disponible en: http://www.cancer.gov/cancertopics/pdq/treatment/neuroblastoma/healthprofessional/allpages.
Gilbert J, Haber M, Bordow SB, Marshall GM, Norris MD. Use of tumor-specific gene expression for the differential diagnosis of neuroblastoma from other pediatric small round-cell malignancies. Am J Pathol. 1999;155:17-21.
Jaffe N, Huff V. Neoplasias renales. En: Behrman RE, Kliegman RM, Jenson HB, editores. Tratado de pediatría de Nelson. 17ma ed. Madrid: Elsevier España; 2004. p. 1711-4.
Paulino AC, Coppes MJ. Wilms tumor [monografía en Internet]. Omaha: eMedicine.com, Inc; 2003 [citado 20 de noviembre de 2005]. Disponible en: http://www.emedicine.com/ped/topic2440.htm.
Grosfeld JL. Risk-based management of solid tumors in children. Am J Surg. 2000;180:322-7.
Gilchrist GS. Linfoma. En: Behrman RE, Kliegman RM, Jenson HB, editores. Tratado de pediatría de Nelson. 17ma ed. Madrid: Elsevier España; 2004. p. 1698-702.
Levine LS, White PC. Feocromocitoma. En: Behrman RE, Kliegman RM, Jenson HB, editores. Tratado de pediatría de Nelson. 17ma ed. Madrid: Elsevier España; 2004. p. 1919-20.
Cripe TP. Rhabdomyosarcoma [monografía en internet]. Omaha: eMedicine.com, Inc; 2004 [citado 20 de noviembre de 2005]. Disponible en: http://www.emedicine.com/ped/topic2005.htm.
Kline N, Sevier NE. Solid tumors in children. J Pediatr Nurs. 2003;18:96-102.
Kennedy JG, Frelinghuysen P, Hoang BH. Ewing sarcoma: current concepts in diagnosis and treatment. Curr Opin Pediatr. 2003;15:53-7.
Henry MC, Tashjian DB, Breuer CK. Neuroblastoma update. Curr Opin Oncol. 2005;17:19-23.

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[1] Wood M, Abinun M, Foster H. Pyrexia of unknown origin. Arch Dis Child Ed Pract. 2004;89:63-9.

[2] Lee YH, Lee HD, Lee YA, Lee YS, Jung JA, Hwang GG et al. Ganglioneuroblastoma presenting as dilated cardiomyopathy. Arch Dis Child. 2003;88:162-4.

[3] Parker L, Craft AW, Brennan BMD, Eden OB. Preclinical diagnosis of abdominal tumours by ultrasound examination. Arch Dis Child. 1998;79:379.

[4] Woods WG, Tuchman M, Robison LL, Bernstein M, Leclerc JM, Brisson LC, et al. A population-based study of the usefulness of screening for neuroblastoma. Lancet. 1996;348:1682-7.

[5] Castleberry RP. Biology and treatment of neuroblastoma. Pediatr Clin North Am. 1997;44:919-37.

[6] Maris JM. The biologic basis for neuroblastoma heterogeneity and risk stratification. Curr Opin Pediatr. 2005;17:7-13.

[7] Ater JL. Neuroblastoma. En: Behrman RE, Kliegman RM, Jenson HB, editores. Tratado de pediatría de Nelson. 17ma ed. Madrid: Elsevier España; 2004. p. 1709-11.

[8] Ferris i Tortajada J, Ortega Garcia JA, Garcia i Castell J, Lopez Andreu JA, Crehuá Gaudiza E. Risk factors for neuroblastoma. An Pediatr (Barc). 2005;63:50-60.

[9] Schofield D, Cotran RS. Enfermedades durante la lactancia y la niñez. En: Cotran RS, Kumar V, Collins T, editores. Patología estructural y funcional. 6ta ed. México: McGraw-Hill Interamericana; 2000. p. 512-5.

[10] National Cancer Institute. Neuroblastoma PDQ®: Treatment [monografía en Internet]. U.S. National Institutes of Health [actualizado 22 jul 2005; citado 19 sept 2005]. Disponible en: http://www.cancer.gov/cancertopics/pdq/treatment/neuroblastoma/healthprofessional/allpages.

[11] Gilbert J, Haber M, Bordow SB, Marshall GM, Norris MD. Use of tumor-specific gene expression for the differential diagnosis of neuroblastoma from other pediatric small round-cell malignancies. Am J Pathol. 1999;155:17-21.

[12] Jaffe N, Huff V. Neoplasias renales. En: Behrman RE, Kliegman RM, Jenson HB, editores. Tratado de pediatría de Nelson. 17ma ed. Madrid: Elsevier España; 2004. p. 1711-4.

[13] Paulino AC, Coppes MJ. Wilms tumor [monografía en Internet]. Omaha: eMedicine.com, Inc; 2003 [citado 20 de noviembre de 2005]. Disponible en: http://www.emedicine.com/ped/topic2440.htm.

[14] Grosfeld JL. Risk-based management of solid tumors in children. Am J Surg. 2000;180:322-7.

[15] Gilchrist GS. Linfoma. En: Behrman RE, Kliegman RM, Jenson HB, editores. Tratado de pediatría de Nelson. 17ma ed. Madrid: Elsevier España; 2004. p. 1698-702.

[16] Levine LS, White PC. Feocromocitoma. En: Behrman RE, Kliegman RM, Jenson HB, editores. Tratado de pediatría de Nelson. 17ma ed. Madrid: Elsevier España; 2004. p. 1919-20.

[17] Cripe TP. Rhabdomyosarcoma [monografía en internet]. Omaha: eMedicine.com, Inc; 2004 [citado 20 de noviembre de 2005]. Disponible en: http://www.emedicine.com/ped/topic2005.htm.

[18] Kline N, Sevier NE. Solid tumors in children. J Pediatr Nurs. 2003;18:96-102.

[19] Kennedy JG, Frelinghuysen P, Hoang BH. Ewing sarcoma: current concepts in diagnosis and treatment. Curr Opin Pediatr. 2003;15:53-7.

[20] Henry MC, Tashjian DB, Breuer CK. Neuroblastoma update. Curr Opin Oncol. 2005;17:19-23.

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