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Introduction. The term Cushing's syndrome is used to describe a condition resulting from prolonged exposure to excessive glucocorticoids. The most common cause is exogenous administration of corticoids. If the cause of the syndrome is an alteration in the anterior pituitary like a pituitary adenoma, it is called Cushing's disease, which is the most common cause once you have been ruled out the excesive of corticoids in these patients.
Case report. We present the case of a 25 year-old man, previously healthy who presented a history of 7 months of evolution characterized by tachycardia, arterial hypertension, proximal muscle weakness, abdominal striae, moon face, hump back, blurred vision, neurological, musculoskeletal, skin and hearing alterations. Physical examination revealed a whole series of changes that raised suspicions of a characteristic clinical syndrome. Diagnostic tests showed positive results for a possible pituitary cause and a brain magnetic resonance was performed, with a mass of 6 mm in the anterior pituitary that slightly distorts the structure of the pituitary gland, confirming the diagnosis of the patient as Cushing's disease.
Discussion. Paramount in the diagnosis of Cushing's syndrome is the presence of hypercortisolism and its etiology, since treatment of this syndrome varies according to the etiology that caused the hypercortisolism.
