Stress is defined as the link mechanism between a stressor agent and its target organ, resulting in a psychophysiological response, characterized by glucocorticoid release. In this study, we review the main effects of stress on the nervous and endocrine systems, as well as the relationship between stress and diet. When experiencing a stressful event, an increase in the corticotropin releasing factor is generated in the hypothalamus, which upon reaching the anterior lobe of the pituitary promotes the secretion of adrenocorticotropic hormone, the latter will finally act on the adrenal gland cortex, inducing glucocorticoids release. The hypothalamic-pituitary-adrenocortical axis, when stimulated by stressful events, causes the increase in of glucocorticoids that promote food intake, particularly high-calorie foods. This intake turns out to be used by individuals as a way of coping with stress and finally inducing obesity.
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