ENFERMEDAD DE KAWASAKI EN PACIENTE DE 20 MESES DE EDAD.

Jocelyn Díaz De Arco; Lissette Raquel Chang

Submitted October 30, 2024

Published 2026-04-06

Artículos de Investigación

Vol. 19 No. 1 (2006): Revista Médico Cientifica

KAWASAKI DISEASE IN A 20 MONTH OLD PATIENT.

Jocelyn Díaz De Arco⁺⁻
Lissette Raquel Chang ⁺⁻

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Published: 2026-04-06

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Díaz De Arco J, Chang LR. KAWASAKI DISEASE IN A 20 MONTH OLD PATIENT. . rmc [Internet]. 2026 Apr. 6 [cited 2026 Oct. 18];19(1):37-43. Available from: https://revistas.up.ac.pa/index.php/revistamedicocientifica/article/view/6166

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Abstract

Kawasaki disease is an acute pathology with an unknown etiology: characterized by fever of five days or more, polymorphous exanthema, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, in children less than four years. We present a case study of a 20 month old patíent with the following c1inic characteristics: fever, rash of the distal extremities with central progression, associated prurítus, congestíon of the ocular conjunctivae and edema in hands and feet. Treatment consisted on the application of intravenous gammaglobulin to which fever persisted 48 hours later with vasculitís, reason why a second applícation is ad'ministrated wíth the expected results. The echocardiograph and radiograph findings didn't reveal further complications.

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References

Sáez-Llorens X. Infectología Práctica para el Pediatra. 1ra ed. Panamá: Sibauste; 2001. pp. 45-6.
Hospital del Niño (Pma). Normas y Protocolo de Manejo de Problemas Pediátricos. Panamá; 2004.
Shulman S, Inocencio J, Hirsch R. Kawasaki disease. Pediatr Clin North Am. 1995; 42:1205-22.
Cassidy J, Petty R. Vasculitis. En: Textbook of pediatric rheumatology, 3rd ed. Philadelphia: WB Saunders Company, 2001 :365-422.
Newburger JW. Kawasaki disease. Current treatment options. Cardiovasc Med. 2000;2:227-36.
Prego J. Enfermedad de Kawasaki. Arch Pediatr Urug. 2003; 74(2): 99-113. disponible en: URL: www.sup.org.uy/Archivos/ Adp74-2/pdf/adp74-2_6.pdf
Levin M, Tizard EJ, Dillon MJ. Kawasaki disease: recent advances. Arch Dis Child. 1991; 66: 1369-74.
López E. Enfermedad de Kawasaki. En: López E. Manual Práctico de Infectología Pediátrica. 2da ed. Buenos Aires: Guido; 1999. p. 103-6
Rowley A, Shulman, S. Rheumatic Diseases of Childhood (Connective Tissue Diseases, Collagen Vascular Diseases). In: Nelson W, Sehrman R, Kliegman, Arvin A, eds. Nelson Textbook of Pediatrics. 17va ed. Estados Unidos: McGrawHill; 2003. p. 823-6.
Tizard EJ. Complications of Kawasaki disease. Curr Pediar. 2005; 15(1): 62-8
Michie C, Kinsler V, Tulloh R, Davidson S. Recurrent skin peeling following Kawasaki disease. Arch Dis Child. 2000; 83(4): 353-5.
Garty S, Mosseri R, Finkelstein Y. Guttate psoriasis following Kawasaki disease. Pediatr Dermatol. 2001; 18 (6): 507-8.
Tori C, Vergas M. Enfermedad de Kawasaki: Un caso con pseudo-obstrucción intestinal y aneurisma gigante. Rev Med Hered. [online]. July/set 2002, vo1.13, nO.3 [cited 14 September 2005], p.114-122. Available from World Wide Web: . ISSN 1018130X.
Rider L. Rheumatology. In: Rudolph C, Rudolph A, Hostetter M, Lister G, Siegel N, editors. Rudolph's Pediatrics. 21 51 ed. Estados Unidos: McGraw-Hill; 2003. p. 853-6
Watanabe T, Iwabuch H. Abe Rhabdomyolyis in a patient with Kawasaki disease. Eur J Paediatr. 2003;162(12): 891-2
Oates-Whitehead RM, Saumer JH, Haines L, Love S, Maconochie IK, Gupta A, et al. Intravenous immunoglobulin for the treatment of Kawasaki disease in children. The Cochrane Database of Systematic Reviews 2003, Issue 4. Art. No.: CD004000. 001: 10.1002/14651858.CD004000.
Han RK, Silverman E, Newman A, Mc Criad le Sw. Management and outcome of persistent or recurrent fever after initial intravenous gamma globulin therapy in acute Kawasaki Disease. Arch Pediatr Adolesc Med 2000; 154 (7): 694-9.
Fulton O, Newburger J. Long term cardiac sequelae of Kawasaki disease, Curr Rheumatol Rep. 2000; 2 (4):324-9
Kato H, Kioke S, Yokayana 1. Kawasaki disease: effect of treatment on coronary artery involvement. Pediatrics. 1979; 63 (2): 175-9.
Wright O, Newburge J, Sake A. Sumde R. Treatment of immune-globulin resistant Kawasaki disease with pulsed doses of corticosteroids. J Pediatr. 1996; 128(1): 146-9.
Dale R, Saleem M, Daw S, Dillon M. Treatment of severe complicated Kawasaki disease with oral prednisolone and aspirin. J Pediatr. 2000; 137(5): 723-6

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[1] Sáez-Llorens X. Infectología Práctica para el Pediatra. 1ra ed. Panamá: Sibauste; 2001. pp. 45-6.

[2] Hospital del Niño (Pma). Normas y Protocolo de Manejo de Problemas Pediátricos. Panamá; 2004.

[3] Shulman S, Inocencio J, Hirsch R. Kawasaki disease. Pediatr Clin North Am. 1995; 42:1205-22.

[4] Cassidy J, Petty R. Vasculitis. En: Textbook of pediatric rheumatology, 3rd ed. Philadelphia: WB Saunders Company, 2001 :365-422.

[5] Newburger JW. Kawasaki disease. Current treatment options. Cardiovasc Med. 2000;2:227-36.

[6] Prego J. Enfermedad de Kawasaki. Arch Pediatr Urug. 2003; 74(2): 99-113. disponible en: URL: www.sup.org.uy/Archivos/ Adp74-2/pdf/adp74-2_6.pdf

[7] Levin M, Tizard EJ, Dillon MJ. Kawasaki disease: recent advances. Arch Dis Child. 1991; 66: 1369-74.

[8] López E. Enfermedad de Kawasaki. En: López E. Manual Práctico de Infectología Pediátrica. 2da ed. Buenos Aires: Guido; 1999. p. 103-6

[9] Rowley A, Shulman, S. Rheumatic Diseases of Childhood (Connective Tissue Diseases, Collagen Vascular Diseases). In: Nelson W, Sehrman R, Kliegman, Arvin A, eds. Nelson Textbook of Pediatrics. 17va ed. Estados Unidos: McGrawHill; 2003. p. 823-6.

[10] Tizard EJ. Complications of Kawasaki disease. Curr Pediar. 2005; 15(1): 62-8

[11] Michie C, Kinsler V, Tulloh R, Davidson S. Recurrent skin peeling following Kawasaki disease. Arch Dis Child. 2000; 83(4): 353-5.

[12] Garty S, Mosseri R, Finkelstein Y. Guttate psoriasis following Kawasaki disease. Pediatr Dermatol. 2001; 18 (6): 507-8.

[13] Tori C, Vergas M. Enfermedad de Kawasaki: Un caso con pseudo-obstrucción intestinal y aneurisma gigante. Rev Med Hered. [online]. July/set 2002, vo1.13, nO.3 [cited 14 September 2005], p.114-122. Available from World Wide Web: . ISSN 1018130X.

[14] Rider L. Rheumatology. In: Rudolph C, Rudolph A, Hostetter M, Lister G, Siegel N, editors. Rudolph's Pediatrics. 21 51 ed. Estados Unidos: McGraw-Hill; 2003. p. 853-6

[15] Watanabe T, Iwabuch H. Abe Rhabdomyolyis in a patient with Kawasaki disease. Eur J Paediatr. 2003;162(12): 891-2

[16] Oates-Whitehead RM, Saumer JH, Haines L, Love S, Maconochie IK, Gupta A, et al. Intravenous immunoglobulin for the treatment of Kawasaki disease in children. The Cochrane Database of Systematic Reviews 2003, Issue 4. Art. No.: CD004000. 001: 10.1002/14651858.CD004000.

[17] Han RK, Silverman E, Newman A, Mc Criad le Sw. Management and outcome of persistent or recurrent fever after initial intravenous gamma globulin therapy in acute Kawasaki Disease. Arch Pediatr Adolesc Med 2000; 154 (7): 694-9.

[18] Fulton O, Newburger J. Long term cardiac sequelae of Kawasaki disease, Curr Rheumatol Rep. 2000; 2 (4):324-9

[19] Kato H, Kioke S, Yokayana 1. Kawasaki disease: effect of treatment on coronary artery involvement. Pediatrics. 1979; 63 (2): 175-9.

[20] Wright O, Newburge J, Sake A. Sumde R. Treatment of immune-globulin resistant Kawasaki disease with pulsed doses of corticosteroids. J Pediatr. 1996; 128(1): 146-9.

[21] Dale R, Saleem M, Daw S, Dillon M. Treatment of severe complicated Kawasaki disease with oral prednisolone and aspirin. J Pediatr. 2000; 137(5): 723-6

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