PARÁLISIS PERIÓDICA TIROTÓXICA. PRESENTACIÓN DE UN CASO

Efraín Pérez; Karen Courville

Submitted November 5, 2024

Published 2026-04-06

Artículos de Investigación

Vol. 15 No. 1 (2002): Revista Médico Científica

THYROTOXIC PERIODIC PARALYSIS: A CASE REVIEW

Efraín Pérez⁺⁻
Karen Courville⁺⁻

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Published: 2026-04-06

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Abstract

This is a case of a 26-year-old patient of Asiatic origin, complaining of a sudden onset of flaccid weakness of upper and lower extremities and a general loss of reflexes, plus diminished potassium blood levels. During the physical examination, signs of hyperthyroidism were found, tests were made to confirm this and treatment was given. Hypokalemia disappeared with the initial treatment, as well as the other symptoms. These findings of hyperthyroidism, flaccid paralysis, and hypokalemia made us believe in a possible thyrotoxic periodic paralysis, infrequent and easily overlooked due to its low incidence and easily diagnosed by its clinical characteristics.

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References

Carod R, Delgado R. Parálisis periódica tirotóxica. Presentación de dos casos. Rev Neurol. 1999;29:510-2.
Avakian M, Foote J, Crapo L. Clinical and metabolic features of thyrotoxic periodic paralysis in 24 episodes. Arch Intern Med. 1999;159:601-6.
Ober K. Thyrotoxic periodic paralysis in the United States. Report of 7 cases and review of the literature. Medicine. 1992;71:109-118.
Adams R, Víctor M, Ropper A. Principles of neurology. 6th ed. New York: McGraw Hill; 1997. p.1441.
Magsino C, Ryan J. Thyrotoxic periodic paralysis. South Med J. 2000;93:996-1003.
Adams R, Victor M, Ropper A. Principles of neurology. 6th ed. New York: McGraw Hill; 1997. p.1485.
Mendell J, Griggs R, Ptácek L. Diseases of muscle. Disorders of unknown pathogenetic mechanism. In: Fauci A, Braunwald E, Isselbacher K, Wilson J, Martin J, Kasper D, et al. Harrison's Principles of Internal Medicine. 14th ed. New York: McGraw Hill; 1998. p.2483.
Brensilver J, Goldberger E. A primer of water, electrolyte and acid-base syndromes. 8th ed. Philadelphia: FA Davis Company; 1996. p.276-7.
Krishma G, Steigerwalt S, Pikus R, Kaul R, Narins R, Raymond K, et al. Hipokalemic states. In: Narins R. Clinical disorders of fluid and electrolyte metabolism. 5th ed. New York: McGraw Hill; 1994. p.669.

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[1] Carod R, Delgado R. Parálisis periódica tirotóxica. Presentación de dos casos. Rev Neurol. 1999;29:510-2.

[2] Avakian M, Foote J, Crapo L. Clinical and metabolic features of thyrotoxic periodic paralysis in 24 episodes. Arch Intern Med. 1999;159:601-6.

[3] Ober K. Thyrotoxic periodic paralysis in the United States. Report of 7 cases and review of the literature. Medicine. 1992;71:109-118.

[4] Adams R, Víctor M, Ropper A. Principles of neurology. 6th ed. New York: McGraw Hill; 1997. p.1441.

[5] Magsino C, Ryan J. Thyrotoxic periodic paralysis. South Med J. 2000;93:996-1003.

[6] Adams R, Victor M, Ropper A. Principles of neurology. 6th ed. New York: McGraw Hill; 1997. p.1485.

[7] Mendell J, Griggs R, Ptácek L. Diseases of muscle. Disorders of unknown pathogenetic mechanism. In: Fauci A, Braunwald E, Isselbacher K, Wilson J, Martin J, Kasper D, et al. Harrison's Principles of Internal Medicine. 14th ed. New York: McGraw Hill; 1998. p.2483.

[8] Brensilver J, Goldberger E. A primer of water, electrolyte and acid-base syndromes. 8th ed. Philadelphia: FA Davis Company; 1996. p.276-7.

[9] Krishma G, Steigerwalt S, Pikus R, Kaul R, Narins R, Raymond K, et al. Hipokalemic states. In: Narins R. Clinical disorders of fluid and electrolyte metabolism. 5th ed. New York: McGraw Hill; 1994. p.669.

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