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Takayasu's arteritis is a chronic vasculitis of large vessels, occurring in the aorta and its main branches. We present the case of a 57-year-old female, who went to the Complejo Hospitalario Dr. Arnulfo Arias Madrid due to stabbing chest pain and numbness of the upper and lower left limbs. A difference in blood pressure was found between both arms, with the absence of Korotkoff sounds in the left arm; the left radial and brachial pulses were absent, and the intensity of the left pedal pulse was decreased. Among the studies, the arteriography of the supra-aortic trunks stands out, showing absence of the right common carotid artery and right vertebral artery, dilatation of the right subclavian artery, and stenosis (82%) of the left subclavian artery and left common carotid artery. The rheumatology service confirmed the diagnosis of Takayasu's arteritis and treated with methotrexate and scheduled a surgery for carotid stent placement.