An experiment was carried out in Naranjal district of Chepo, Panama, Republic of Panama. The objective was to establish the nutritional and productive effects of sowing distances and prune frequencies upon morera shrub (Morus alba). Three replications in a complete block with a 3x3 factorial arrangement experimental design were used. Distances among plants were 0.4, 0.5 and 0.6 m, and prune frequencies from morera sprout were 8, 12 and 16 weeks at 0.4 m height. The mean plant height and dry matter forage yield were increasing as sowing distances and prune frequencies increased. Sowing distances and prune frequencies effects were highly significant (P<0.01) over whole plant, stalk and leave dry matter forage yield. Raw protein and in vitro digestibility values were significant (P<0.05) for the pruning frequencies only, were increases in the cutting intervals, diminish their contents.