This study reports a new record for Tylomys panamensis, increasing its range by 121 km, 66º NW from the original endemic distribution.  It has been considered as Data Deficient by IUCN as no information has been published for almost 64 years. Based on our long term surveillance at the Darien’s canopy, using Orion Camera System (OCS), we have been able to obtain information about their circadian and monthly activity over the course of one year. The presence of T. panamensis remarks the importance of the largest National Park of the Mesoamerican region and claim urgency to be protected from its actual devastation, particularly the montane forest in the rest of the provinces of Darien and Panama.