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About nature and sense experience, what foundations do we find in Kant's transcendental aesthetics and Don Ihde's philosophy of technology, and how can these be related? In this regard, this paper seeks, through the reconstruction and propositional interpretation, approaches to epistemological perspectives about the experience of sensible knowledge and the relationship with nature, in a Kant-Ihde dialogue, to observe how there are different forms of approach to conception and relationships with nature whether mediated or not by experience, whether mediated or not by technology.