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Covid-19 generated an unprecedented economic and health crisis, making Panama one of the countries with the greatest economic contraction in the Latin American Region, only surpassed by Peru and Venezuela. As of 2021, the recovery process begins with good growth prospects linked mainly to the “geographical vocation and the transitory nature of the Panamanian economy” (Calvo, 2014); however, great social and territorial inequalities are identified, regions disconnected from the development and economic growth that is generated in the provinces near the canal area, Panama, Colon and West Panama, and which concentrate more than 83.1% of the national income; On the other hand, we find provinces such as Bocas del Toro, Darién and Los Santos, which, as a whole, barely participate with 3.2% of the national wealth, a high unemployment rate and rampant informality that by 2021 is close to 63% of the occupied population. At this juncture of the Panamanian economy, the Covid-19 and the Sustainable Development Goals (SDGs), this study aims to propose the Circular Economy as an alternative to achieve a more inclusive, more resilient and sustainable economic development, which integrates economic and geographically throughout the country.