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This article analyzes public ethics and institutional integrity as preventive mechanisms against administrative corruption in the Panamanian public sector. Administrative corruption undermines citizens' trust, weakens public institutions, and hinders the equitable distribution of public resources, affecting democratic governance and sustainable development. Using a qualitative, documentary, and analytical research approach, the study reviews recent scientific literature, international reports, and the Panamanian legal framework related to transparency, accountability, public integrity, and open government. The findings indicate that combating corruption requires moving beyond punitive approaches toward comprehensive preventive strategies based on ethical values, professional public service, institutional risk management, transparency, citizen participation, and accountability. The analysis concludes that strengthening institutional integrity is essential for improving public administration, promoting equity, and restoring public trust. In the Panamanian context, consolidating an ethical culture within public institutions is a strategic condition for ensuring responsible governance, protecting the public interest, and reinforcing democratic institutions.