This essay presents our reflections on the construction of the relationship between intersubjectivity and the world of life, as understanding of social actors or people, which give meaning to the phenomena and / or objects. In the same way we emphasized the importance that intersubjectivity   has in nursing research, because, when looking at intersubjectivity has a human process, to understand the meanings of the social construct of a phenomena, the nurse can obtain knowledge from a loaded reference of nuances that avoid reducing the human being to a simple spectator during the investigation, making him or she participant as well as the researcher. The intersubjectivity, without doubts, has opened a new way so that research in nursing crosses new passages by means of the interpretive paradigm, in those scenes in which they are involved in nursing care.