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Introduction: On March 11, 2020, the World Health Organization (WHO) declared COVID-19 a pandemic due to its rapid spread, leading to a progressive collapse of health systems globally. In Panama, the first case was detected on March 8, 2020. As of March 24, the country adopted the strategy of using hotels for the isolation of positive or suspected patients, an initiative led by Nurses. The objective of the study was to describe the characteristics of patients with COVID-19 cared for by nurses at the Hospital Hotels in the capital of Panama. Methodology: This observational, descriptive, and retrospective study included 18,510 patients with a positive diagnosis for SARS-CoV-2 admitted between March 2020 and June 2022. Results and discussion: Among the 18,510 patients, 62.52% were men and 37.48% were women. The age group with the highest income for both men and women was 25 to 29 years old. Most patients (73.25%) had no pathological history, while of those who did, arterial hypertension was the most common with 8.95%. The main condition of discharge was that of clinical recoveries (89.09%). A predominance of young patients with no pathological history is observed. Vaccination proved to be effective and no deaths were reported in vaccinated patients after their transfer. Conclusion: The strategy was successful in containing cases and decongesting the health system.
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