Within the context of religious tourism, a modality motivated by the desire to attend events or know religious destinations, the World Youth Day (WYD) was celebrated in Panama City in January 2019. This event, held every three years, took place between 22 and 27, and according to information provided by the official site of WYD Panama 2019, gathered more than 700,000 people. With an event of such magnitude, questions arise about the impacts on different sectors of the country, this question is addressed in this exploratory documentary research with respect to the hotel sector of Panama City. The press releases found on the subject were contrasted with official documents of the World Tourism Organization and research articles on other successful cases of religious tourism in the Ibero-American area. The article concludes on the positive economic and marketing effects for the hotel sector but also underlines the need to systematize the required information and the implementation of tourist market intelligence systems and the satellite account.