This paper explained the special protection provided to the cardholder in Panamanian legislation, in the face of Law 81 of 2009. First, a study of the relevant doctrine on the subject was carried out, especially the conceptual definitions of the contract of credit card and the cardholder. The regulations contained in Law 81 of 2009 were also interpreted, based on the exegetical method, with emphasis on the protection and rights provided by the law to the consumer of credit cards. The article includes a description of the main advances in defense of the user presented in the Panamanian regulation, such as the obligation of the banking entities to clearly inform users about their rights. The main conclusion is that the regulation is a significant advance in the recognition of rights of credit card´s users issued by banks, although it missed the opportunity to include in the object of the law all credit card users and also, to placing the claims of all users under the competence of the Consumer Protection and Competition Defense Authority ACODECO.