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Primary Aldosteronism is an entity characterized by excessive production of aldosterone independent from the renin-angiotensin-aldosterone system. The most common clinical presentation of Primary Aldosteronism is Resistant Hypertension. About 10% of secondary hypertension cases are associated to Primary Aldosteronism, in which 50% of cases is due to an adrenal adenoma. This case is about a 53-year-old male with history of arterial hypertension of 11 years of evolution with difficult control, studied for presenting muscle cramps, fatigue and hypokalemia. On suspicion of Primary Aldosteronism, Aldosterone-to-Renin Ratio test is done, which is found elevated. A laparoscopic adrenalectomy is performed after contrast-enhanced computed tomography findings of a nodular lesion in the right adrenal gland. Histopathological study confirms the diagnosis. The patient has not presented values of arterial hypertension after the surgery.