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INTRODUCTION: Secondary syphilis is a widely studied entity in different populations worldwide, and our country does not escape this reality. However, there is a palpable lack of knowledge in its management in pregnant patients, with high underreporting in our country likely due to insufficient prenatal care by either the patient or physician.
CASE: A 13-year-old primigravida at 23 weeks of pregnancy attended her first prenatal appointment with a 3-month history of maculopapular lesions on all four limbs, the palmar region, back, and chest, as well as condylomatous lesions in the perianal and vulvar regions. Given the clinical presentation, a non-treponemal test was conducted, reporting titers of 1:32. Subsequently, the MHATP test confirmed the diagnosis with a positive result. Obstetrical ultrasound showed no findings suggestive of fetal infection. Benzathine penicillin G was administered intramuscularly, totaling 7.2 million IU, divided into three weekly doses of 2.4 million IU, resulting in a decrease in serologic titers.
CONCLUSION: Maternal screening during prenatal care and recognition of this disease are key in the early treatment of pregnant women to avoid fetal complications during pregnancy. Similarly, this approach helps reduce underreporting and supports the development of health policies that benefit pregnant women more broadly.
