The objective of the study was to evaluate the influence of breed, season of the year, month and time of day on the physiological and productive responses of dairy goats in a humid tropical climate in Panama. 20 animals were used, 10 goats for each breed. The animals were managed in a stable system and evaluated from January to August 2022. There were differences (P<0.05) observed for the ITH temperature and humidity index, which indicated that the hours from 12:00 to 1:00 p.m. (noon) presented a higher ITH with 79.57 during the dry season and 79.39 during the rainy season, compared to the hours from 6:00 to 7:00 a.m. and from 4:00 to 5:00 p.m. with ITH 73.62 dry season and 76.13 respectively. While, in the rainy season, from 6:00 to 7:00 and 4:00 to 5:00 p.m. they presented ITH with 73.96 and 78.48 respectively. Respiratory frequency, heartbeat and rectal temperature did not present significant differences (p> 0.05) between the races, however, there was a different behavior in the months and hours (p<0.05). The goats presented average daily production of 1.85 ± 0.05 kg Saanen and 1.65 ± 0.05 kg Parda Alpina and accumulated production at 250 days, 482.0 ± 41.26 kg Saanen breed and 365.0 ± 39.08 kg Alpine Brown. The Saanen and Brown Alpine goat breeds, regardless of the season and month of the year, are susceptible to moderate-high heat stress during noon when the ITH exceeds 77 units in a humid tropical environment.