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This academic work aims to conduct a systematic documentary review of teaching and learning methodologies, high-fidelity simulation, that contribute to the development of competencies and professional expertise among nursing students. Methodologically, this is a qualitative, descriptive study based on the analysis of formal written and electronic sources related to the topic studied. This review seeks to generate meaningful knowledge that strengthens the educational process in the health sciences, promoting competency development through practical action in simulated environments. The adopted approach ensures a high probability of achieving learning objectives and developing professional expertise by allowing students to face complex clinical situations in a safe and controlled environment. The authors use this theoretical and methodological foundation to contribute to knowledge that enriches academic and dialectical processes in society. In conclusion, as the use of high-fidelity simulators increases in nursing education, the likelihood grows that future professionals will work with greater efficiency and more adaptability in their professional environments. This not only improves care processes but also allows services to be safer, more humanized, and more effective, with significant benefits for patient care quality.