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This scientific article synthesizes the influence of the work environment on the motivation of employees from the highest-ranking companies in Panama, as recognized by the Corporate Reputation Business Monitor (MERCO).The type of study corresponds to non-experimental, descriptive, qualitative research, in which the interview technique is applied to a sample of 50 employees from the three companies, with no supervisory level, selected at random. The findings of this study demonstrate that the three selected companies have put into practice measures that promote a positive work atmosphere for their staff. They adhere strictly to the guidelines of the Professional Code of Ethics and the National Pact for Public-Private Social Responsibility and Human Rights, which are the cornerstones that have enabled Banco General, the Panama Canal Authority, and COPA Airlines to achieve top rankings in MERCO Panama. To ensure these companies remain in their leading positions in Panama, they must maintain an organizational culture anchored in tangible goals, in alignment with the global market, while satisfying their customers and preserving excellent labor relations. The contributions and performance of their employees are crucial for maintaining their economic status, image, and projection as premier brand companies in Panama.