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In the context of Panamanian Criminal Procedural Law, fundamental guarantees represent the essential pillar that supports justice, equity and respect for individual rights throughout the judicial process. The Republic of Panama, committed to respecting human dignity and protecting its citizens, has established a robust legal framework that seeks to reconcile effectiveness in the prosecution of crimes with the preservation of constitutional rights. The discussion on fundamental guarantees in Panamanian Criminal Procedural Law covers a diverse spectrum of principles and regulations that protect the presumption of innocence, the right to a fair trial, personal integrity and other fundamental rights during the different phases of the criminal process. This approach, reflected in the Political Constitution of the Republic of Panama and developed in specific laws, guarantees that the State fulfills its duty to maintain public order without undermining individual freedoms. This analysis delves into the detailed examination of the fundamental guarantees in Panamanian Criminal Procedural Law, incorporating key elements discussed in this dialogue, such as the protection of constitutional guarantees and the writ of Habeas Corpus. Likewise, we will explore how these guarantees not only act as indispensable safeguards for those subjected to criminal proceedings, but also contribute to strengthening confidence in the judicial system and consolidating the rule of law in the Panamanian nation.