Panama, historically positioned as a strategic enclave for international trade and finance, has experienced notable economic growth in recent decades. However, this prosperity has not led to an equitable distribution of wealth, fostering an environment conducive to the misuse of public resources, which is susceptible to corruption. The objective of this study is to analyze the phenomenon of corruption that distorts the Panamanian economy and society by undermining trust in public institutions. To this end, a qualitative and descriptive methodology was adopted, complemented by an explanatory correlational approach, which allowed for the examination of specific cases and patterns of embezzlement and misuse of state resources by individual and collective actors. The results show that the increase in corruption has evolved in parallel with economic growth, negatively impacting public administration and social well-being. The urgent need to establish stricter sanctions and effectively enforce the current legal framework as a deterrent to corrupt practices is underscored. In conclusion, although Panama has made substantial economic progress, its consolidation as an equitable and sustainable society depends critically on strengthening transparency and a determined fight against corruption at all levels of government.