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This paper addresses the crisis of the classical humanist paradigm in the face of the intensification of the technological modification of the human being (BCI, advanced prostheses, AIG). To postulate a new analytical framework, termed co-Enactive Subjectivity, to explain how technologies redefine the constitutive core of subjectivity, agency, and normativity. The research is documentary-exploratory, based on a deductive-inductive qualitative content analysis. It examines the limitations of classical enactivism (Autopoiesis and Allopoiesis) in order to later articulate an alternative theoretical basis in dialogue with Simondon’s theory of individuation and Barad’s performative ontology. Relational Heteropoiesis is proposed as the generative principle and co-enactivation as the operational mechanism of the new subjective system. This framework overcomes strict biological closure and the deception of exteriority by recognizing the constitutive dependence and phenomenological incorporation of heteropoietic elements. co-enactive subjectivity emerges as a hybrid and metastable assemblage, demanding the formulation of an ethics that transcends individual responsibility, focused on principles of algorithmic transparency, reversibility due to structural precariousness, and justice of access in the face of technological asymmetries.