INTERACCIÓN DE PROROCENTRUM LIMA CON LAS MACROALGAS AGAROPHYTON CHILENSIS, ULVA SPP. Y CODIUM FRAGILE Y SU EFECTO EN LA ESTIMULACIÓN DEL EPIFITISMO

Roberto Pino Selles; Eduardo Uribe; Gonzalo Álvarez

doi:10.48204/j.tecno.v26n1.a4650

Submitted January 18, 2024

Published 2024-01-24

Artículos

Vol. 26 No. 1 (2024): Tecnociencia

INTERACTION OF PROROCENTRUM LIMA WITH THE MACROALGAE AGAROPHYTON CHILENSIS, ULVA SPP. AND CODIUM FRAGILE AND ITS EFFECT ON THE STIMULATION OF EPIPHYTISM

Roberto Pino Selles ⁺⁻
Eduardo Uribe ⁺⁻
Gonzalo Álvarez ⁺⁻

DOI https://doi.org/10.48204/j.tecno.v26n1.a4650

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References

DOI: 10.48204/j.tecno.v26n1.a4650

Published: 2024-01-24

How to Cite

Pino Selles , R., Uribe , E. and Álvarez , G. (2024) “INTERACTION OF PROROCENTRUM LIMA WITH THE MACROALGAE AGAROPHYTON CHILENSIS, ULVA SPP. AND CODIUM FRAGILE AND ITS EFFECT ON THE STIMULATION OF EPIPHYTISM”, Tecnociencia, 26(1), pp. 60–91. doi: 10.48204/j.tecno.v26n1.a4650.

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Abstract

Prorocentrum lima has presented frequent studies in the aquaculture area, within security control of bivalve mollusks. This dinoflagellate has not been cultivated on a large scale in an autotrophic framework with inorganic culture media. The present study seeks to understand its epiphyte-benthic character and its interactions with some macroalgae to develop new technologies and cultivate it on a large scale. The P. lima strain was isolated from Codium fragile, and in culture with inorganic medium its maximum cell density (20 317 cells mL^-1) was obtained on day 24, with an average growth rate of 0.0815 ± 0.2027 div day^-1. In a mesocosm culture simulation under natural and controlled environmental conditions, P. lima epiphyted the macroalgae Agarophyton chilensis, Ulva spp. and C. fragile, in addition to all the inert structures present in the culture ponds. However, it presented the highest density (80 053 cells g^-1 FW) on A. chilensis, under controlled conditions at 13 days of culture. The macroalgae would be providing specific organic nutrients that would stimulate the growth of P. lima.

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Águila-Ramírez, R., Arenas-González, A., Hernández-Guerrero, C., González-Acosta, B., Borges-Souza, J., Véron, B., & Hellio, C. (2012). Antimicrobial and antifouling activities achieved by extracts of seaweeds from Gulf of California, Mexico. Hidrobiologica, 22(1), 8–15.
Aligizaki, K., & Nikolaidis, G. (2006). The presence of the potentially toxic genera Ostreopsis and Coolia (Dinophyceae) in the North Aegean Sea, Greece. Harmful Algae, 5(6), 717–730
https://doi.org/10.1016/j.hal.2006.02.005
Aligizaki, K., & Nikolaidis, G. (2008). Morphological identification of two tropical dinoflagellates of the genera Gambierdiscus and Sinophysis in the Mediterranean Sea. Journal of Biological Research, 9, 75–82.
Aligizaki, K., Nikolaidis, G., Katikou, P., Baxevanis, A., & Abatzopoulos, T. (2009). Potentially toxic epiphytic Prorocentrum (Dinophyceae) species in Greek coastal waters. Harmful Algae, 8(2), 299–311.https://doi.org/10.1016/j.hal.2008.07.002
Aquino-Cruz, A., Purdie, D., & Morris, S. (2018). Effect of increasing sea water temperature on the growth and toxin production of the benthic dinoflagellate Prorocentrum lima. Hydrobiologia, 813(1), 103–122. https://doi.org/10.1007/s10750-018-3512-4
Arbeláez, N., Mancera-Pineda, J., & Reguera, B. (2020). Structural variation of potentially toxic epiphytic dinoflagellates on Thalassia testudinum from two coastal systems of Colombian Caribbean. Harmful Algae, 92(January), 101738. https://doi.org/10.1016/j.hal.2019.101738
Aumeerun, S., Soulange-Govinden, J., Driver, M., Rao, A., Ravishankar, G., & Neetoo, H. (2019). Macroalgae and Microalgae. In Handbook of Algal Technologies
and Phytochemicals (p. 207).
Berdalet, E., Fleming, L., Gowen, R., Davidson, K., Hess, P., Backer, L., Moore, S., Hoagland, P. & Enevoldsen, H. (2016). Marine harmful algal blooms, human health and wellbeing: challenges and opportunities in the 21st century. Journal of the Marine Biological Association of the United Kingdom, 96(1), 61–91. https://doi.org/https//: 10.1017/ S00253 15415001733
Bomber, J., & Aikman, K. (1989). The Ciguatera Dinoflagellates. Biological Oceanography, 6, 291–311.
Bomber, J., Guillard, R., & Nelson, W. (1988). Roles of temperature, salinity, and light in seasonality, growth, and toxicity of ciguatera-causing Gambierdiscus toxicus Adachi et Fukuyo (Dinophyceae). J. Exp. Mar. Biol. Ecol., 115, 53–65.
Bomber, J., Rubio, M., & Norris, D. (1989). Epiphytism of dinoflagellates associated with the disease ciguatera: substrate specificity and nutrition. Phycologia, 28(3), 360–368.
https://doi.org/10.2216/i0031-8884-28-3-360.1
Bravo, I., Fernández, M. L., Ramilo, I., & Martínez, A. (2001). Toxin composition of the toxic dinoflagellate Prorocentrum lima isolated from different locations along the Galician coast (NW Spain). Toxicon, 39(10), 1537–1545. https://doi.org/10.1016/S0041-0101(01)00126-X
Bravo, I., Rodríguez, F., Ramilo, I., & Afonso-Carrillo, J. (2020). Epibenthic Harmful Marine Dinoflagellates from Fuerteventura (Canary Islands), with Special Reference to the Ciguatoxin-Producing Gambierdiscus. J. Mar. Sci. Eng., 8, 0909.
Carlson, R., Morey-Gaines, G., Tindall, D., & Dickey, R. (1984). Ecology of Toxic Dinoflagellates from the Caribbean Sea Effects of Macroalgal Extracts on Growth in Culture. Sea Food Toxins, 24, 271–
https://doi.org/doi:10.1021/bk-1984-0262.ch024
Catuto-Magallan, R. (2019). Composición y abundancia de dinoflagelados epibentónicos asociados a macroalgas en dos playas de la Provincia de Santa Elena. Universidad Estatal Península de Santa Elena.
Chandia, P. (2020). Valor agregado a macroalgas chilenas de exportación: caracterización de ficocoloides, denominación de origen y diversificación comercial. Proyecto BBPP 18BPE-93853.
Chinain, M., Germain, M., Deparis, X., Pauillac, S., & Legrand, A. (1999). Seasonal abundance and toxicity of the dinoflagellate Gambierdiscus spp. (Dinophyceae), the causative agent of ciguatera in Tahiti, French Polynesia. Marine Biology, 135, 259–267. https://doi.org/doi: 10.1007/s002270050623
David, H., Laza-Martínez, A., Kromkamp, J. C., & Orive, E. (2018). Physiological response of Prorocentrum lima (Dinophyceae) to varying light intensities. FEMS Microbiology Ecology, 94(1), 1–12. https://doi.org/10.1093/femsec/fix166
Faust, M. (1995). Observation of sand-dwelling toxic dinoflagellates (Dinophyceae) from widely differing sites, incluiding two new species. Journal Phycol., 42, 154–159.
Faust, M. A. (1998). Mixotrophy in tropical benthic dinoflagellates. In: Reguera, B., Blanco, J. Fernandez, L., Wyatt, T. (Eds.) Harmful Algae. Xunta de Galicia and Intergovernmental Oceanographic Commission of UNESCO, Paris, Pp 390-393.
Faust, M., & Gulledge, R. (2004). Identifying Harmful Marine Dinoflagellates. Journal of Applied Phycology, 16(1), 79. https://doi.org/10.1023/b:japh.0000019147.40273.1b
Faust, M. A. (1991). Morphology of Ciguatera-causing Prorocentrum lima (Pyrrophyta) from widely differing sites. J. Phycol., 27, 642–648.
Foden, J., Purdie, D., Morris, S., & Nascimento, S. (2005). Epiphytic abundance and toxicity of Prorocentrum lima populations in the Fleet Lagoon, UK. Harmful Algae, 4, 1063–1074.
https://doi.org/https//:10.1016/j.hal.2005.03.004
Fukuyo, Y. (1981). Taxonomical Study on Benthic Dinoflagellates Collected in Coral Reefs. Bulletin of the Japanese Society of Scientific Fisheries, 47(8), 967–978.
GEOHAB. (2012). Global Ecology and Oceanography of Harmful Algal Blooms, GEOHAB Core Research Project: HABs in Benthic Systems. In A. Berdalet, E., Tester, P., Zingone (Ed.), Organization. IOC of UNESCO and SCOR, Paris and Newark.
Gu, S., Xiao, S., Zheng, J., Li, H., Liu, J., & Yang, W. (2019). ABC Transporters in Prorocentrum lima and Their Expression Under Different Environmental Conditions Including Okadaic Acid Production. Marine Drugs, 17(259), 1–16.
Guillard, R. R. L., & Hargraves, P. E. (1993). Stichochrysis immobilis is a diatom, not a chrysophyte. Phycologia, 32(3), 234–236. https://doi.org/10.2216/i0031-8884-32-3-234.1
Hachani, M. A., Dhib, A., Fathalli, A., Ziadi, B., Turki, S., & Aleya, L. (2018). Harmful epiphytic dinoflagellate assemblages on macrophytes in the Gulf of Tunis. Harmful Algae, 77(June), 29–42.
https://doi.org/10.1016/j.hal.2018.06.006
Hales, S., Weinstein, P., & Woodward, A. (1999). Ciguatera (Fish Poisoning), El Niño, and Pacific Sea Surface Temperatures. Ecosystem Health, 5, 20–25.
https://doi.org/doi: 10.1046/j.1526-0992. 1999. 0990 3.x
Heredia-Tapia, A., Arredondo-Vega, B., Nuñez-Vázquez, E., Yasumoto, T., Yasuda, M., & Ochoa, J. (2002). Isolation of Prorocentrum lima (Syn. Exuviella lima) and diarrhetic shellfish poisoning (DSP) risk assessment in the Gulf of California, Mexico. Toxicon 4, 40, 1121–1127.
Hou, D., Liang, J., Zou, C., Li, H., Liu, J., & Yang, W. (2015). MRP functional activity and character in the dinoflagellate Prorocentrum lima. Journal of Applied Phycology, 28, 1667–1676.
https://doi.org/https//:10.1007/s10811-015-0679-1
Hu, Tingmo, LeBlanc, P., Burton, I. W., Walter, J. A., McCarron, P., Melanson, J. E., Strangman, W., & Wright, J. L. C. (2017). Sulfated diesters of okadaic acid and DTX-1: Self-protective precursors of diarrhetic shellfish poisoning (DSP) toxins. Harmful Algae, 63, 85–93. https://doi.org/10.1016/j.hal.2017.01.012
Hu, W., Xu, J., Sinkkonen, J., & Wu, J. (2010). Polyketides from Marine Dinoflagellates of the Genus Prorocentrum, Biosynthetic Origin and Bioactivity of Their Okadaic Acid Analogues. Mini-Reviews in Medicinal Chemistry, 10, 51–61.
https://doi.org/10.2174/138955710791112541
Irola-Sansores, E. D., Delgado-Pech, B., García-Mendoza, E., Núñez-Vázquez, E. J., Olivos-Ortiz, A., & Almazán-Becerril, A. (2018). Population dynamics of benthic-epiphytic dinoflagellates on two macroalgae from coral reef systems of the northern Mexican Caribbean. Frontiers in Marine Science, 5, 1–14.
https://doi.org/10.3389/fmars.2018.00487
Karafas, S., York, R., & Tomas, C. (2015). Morphological and genetic analysis of the Coolia monotis species complex with the introduction of two new species, Coolia santacroce sp. nov. and Coolia palmyrensis sp. nov. (Dinophyceae). Harmful Algae, 46, 18–33.
https://doi.org/10.1016/j.hal.2015.05.002
Kibler, S. R., Tester, P. A., Kunkel, K. E., Moore, S. K., & Litaker, R. W. (2015). Effects of ocean warming on growth and distribution of dinoflagellates associated with ciguatera fish poisoning in the Caribbean. Ecological Modelling, 316, 194–210.
https://doi.org/10.1016/j.ecolmodel.2015.08.020
Lartigue, J., Jester, E. L. E., Dickey, R. W., & Villareal, T. A. (2009). Nitrogen source effects on the growth and toxicity of two strains of the ciguatera-causing dinoflagellate Gambierdiscus toxicus. Harmful Algae, 8, 781–791. https://doi.org/10.1016/j.hal.2008.05.006
Lassus, P., Chomerat, N., Hess, P., & Nezan, E. (2016). Microalgues toxiques et nuisibles de l’océan mondial. COI Manuels et Guides, 68 / Toxic and Harmful Microalgae of the World Ocean. IOC Manuals and Guides, 68.
Laza-Martinez, A., Orive, E., & Miguel, I. (2011). Morphological and genetic characterization of benthic dinoflagellates of the genera Coolia, Ostreopsis and Prorocentrum from the south-eastern Bay of Biscay. European Journal of Phycology, 46(1), 45–65.
https://doi.org/10.1080/09670262.2010.550387
Lee, S., Hwang, B., Kim, H., Yih, W., & Jeong, E. (2015). A New Diol Ester Derivative of Dinophysistoxin-1 from Cultures of Prorocentrum lima Collected in South Korea. Bulletin of the Korean Chemical Society, 395–398. https://doi.org/10.1002/bkcs.10031
LeGresley, M., & McDermott, G. (2010). Counting chamber methods for quantitative phytoplankton analysis - haemocytometer, Palmer-Maloney cell and Sedgewick-Rafter cell. In Microscopic and molecular methods for Quantitative phytoplankton analysis, 25–30.
Levasseur, M., Thompson, P., & Harrison, P. (1993). Physiological acclimation of marine phytoplankton to different nitrogen sources. J. Phycol., 29, 587–595.
Lewis, N., Wolny, J., Achenbach, J., Ellis, L., Pitula, J., Rafuse, C., Rosales, D. & McCarron, P. (2018). Identification, growth and toxicity assessment of Coolia meunier (Dinophyceae) from Nova Scotia, Canada. Harmful Algae, 75, 45–56.
https://doi.org/10.1016/j.hal.2018.04.001
Litaker, R. W., Vandersea, M. W., Faust, M. A., Kibler, S. R., Nau, A. W., Holland, W. C., Chinain, M., Holmes, M., & Tester, P. A. (2010). Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus. Toxicon, 56(5), 711–730.
https://doi.org/10.1016/j.toxicon.2010.05.017
Lobel, P., Anderson, D., & Durand-Clement, M. (1988). Assessment of Ciguatera Dinoflagellate Populations: Sample Variability and Algal Substrate Selection. The Biological Bulletin, 175(1), 94–101. https://doi.org/10.2307/1541896
López-Rosales, L., Gallardo-Rodríguez, J. J., Sánchez-Mirón, A., Cerón-García, M. del C., Belarbi, E. H., García-Camacho, F., & Molina-Grima, E. (2013). Simultaneous effect of temperature and irradiance on growth and okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum. Toxins, 6(1), 229–253.
https://doi.org/10.3390/toxins6010229
Mangialajo, L., Ganzin, N., Accoroni, S., Asnaghi, V., Blanfuné, A., Cabrini, M., Chavanon, F., Chiantore, M., Cohu, S., Costa, E., Fornasaro, D., Grossel, H., Marco-Miralles, F., Masó, M., Reñé, A., Rossi, A., Sala, M., Thibaut, T., Totti, C., Vila, M., & Lemée, R. (2011). Trends in Ostreopsis proliferation along the Northern Mediterranean coasts. Toxicon, 57(3), 408–420.
https://doi.org/10.1016/j.toxicon.2010.11.019
Marr, J., Hu, T., Pleasance, S., Quilliam, M., & Wright, J. (1992). Detection of new 7-O-acyl derivatives of diarrhetic shellfish poisoning toxins by liquid chromatography-mass spectrometry. Toxicon, 30(12), 1621–1630.
Matsuhiro, B., & Urzúa, C. (1990). Agars from Gracilaria chilensis (Gracilariales). Journal of Applied Phycology, 2(3), 273–279. https://doi.org/https//:10.1007/BF02179785
McLachlan, J. L., Marr, J. C., Conlon?Keily, A., & Adamson, A. (1994). Effects of nitrogen concentration and cold temperature on DSP?toxin concentrations in the dinoflagellate Prorocentrum lima (prorocentrales, dinophyceae). Natural Toxins, 2(5), 263–270.
https://doi.org/10.1002/nt.2620020504
Moreira-González, A. R., Fernandes, L. F., Uchida, H., Uesugi, A., Suzuki, T., Chomérat, N., Bilien, G., & Mafra, L. L. (2018). Variations in morphology, growth, and toxicity among strains of the Prorocentrum lima species complex isolated from Cuba and Brazil. Journal of Applied Phycology, 31(1), 519–532.
https://doi.org/10.1007/s10811-018-1587-y
Morton, S., & Faust, M. (1997). Survey of Toxic Epiphytic Dinoflagellates from the Belizean Barrier Reef Ecosystem. Bulletin of Marine Science -Miami, 61(3), 899–906.
Morton, S., Norris, D., & Bomber, J. (1992). Effect of temperature, salinity and light intensity on the growth and seasonality of toxic dinoflagellates associated with ciguatera. Journal of Experimental Marine Biology and Ecology, 157, 79–90.
https://doi.org/10.1016/0022-0981(92)90076-M
Murakami, Y., Oshima, Y., & Yasumoto, T. (1982). Identification of Okadaic Acid As a Toxic Component of a Marine Dinoflagellate Prorocentrum lima. Nippon Suisan Gakkaishi, 48(1), 69–72. https://doi.org/https//:10.2331/suisan.48.69
Nagahama, Y., Murray, S., Tomaru, A., & Fukuyo, Y. (2011). Species boundaries in the toxic dinoflagellate Prorocentrum lima (Dinophyceae, Prorocentrales), based on morphological and phylogenetic characters. Journal of Phycology, 47(1), 178–189.
https://doi.org/10.1111/j.1529-8817.2010.00939.x
Nakahara, H., Sakami, T., Chinain, M., & Ishida, Y. (1996). The role of macroalgae in epiphytism of the toxic dinoflagellate Gambierdiscus toxicus (Dinophyceae). Phycological Research, 44(2), 113–117. https://doi.org/10.1111/j.1440-1835.1996.tb00385.x
Nascimento, S. M., Purdie, D. A., & Morris, S. (2005). Morphology, toxin composition and pigment content of Prorocentrum lima strains isolated from a coastal lagoon in southern UK. Toxicon, 45(5), 633–649. https://doi.org/10.1016/j.toxicon.2004.12.023
Nascimento, S. M., Salgueiro, F., Menezes, M., Oliveira, F. de A., Magalhães, V. C. P., De Paula, J. C., & Morris, S. (2016). Prorocentrum lima from the South Atlantic: Morphological, molecular and toxicological characterization. Harmful Algae, 57, 39–48.
https://doi.org/10.1016/j.hal.2016.05.006
Nishimura, T., Uchida, H., Noguchi, R., Oikawa, H., Suzuki, T., Funaki, H., hara, C., Hagino, K., Arimitsu, S., Tanii, Y., Abe, S., Hashimoto, K., Mimura, K., Tanaka, K., Yanagida., & I. Adachi, M. (2020). Abundance of the benthic dinoflagellate Prorocentrum and the diversity, distribution, and diarrhetic shellfish toxin production of Prorocentrum lima complex and P. caipirignum in Japan. Harmful Algae, 96, 101687. https://doi.org/10.1016/j.hal.2019.101687
Okolodrov, Y., Merino-Virgilio, F., Aké-Castillo, J., Aguilar-Trujillo, A., Espinoza-Matías, S., & Herrera-Silveira, J. (2014). Seasonal changes in epiphytic dinoflallelate assemblages near the Northern coast ot the Yucatan peninsula, Gulf of Mexico. Acta Botanica Mexicana, 107, 121–151.
Parsons, M., & Preskitt, L. (2007). A survey of epiphytic dinoflagellates from the coastal waters of the island of Hawai’i. Harmful Algae, 6(5), 658–669. https://doi.org/10.1016/j.hal.2007.01.001
Parsons, M., Settlemier, C., & Ballauer, J. (2011). An examination of the epiphytic nature of Gambierdiscus toxicus, a dinoflagellate involved in ciguatera fish poisoning. Harmful Algae, 10(6), 598–605. https://doi.org/10.1016/j.hal.2011.04.011
Paz, B., Vázquez, J., Riobó, P., & Franco, J. (2006). Study of the effect of temperature, irradiance and salinity on growth and yessotoxin production by the dinoflagellate Protoceratium reticulatum in culture by using a kinetic and factorial approach. Marine Environmental Research, 62(4), 286–300.
https://doi.org/10.1016/j.marenvres.2006.04.066
Pearce, I., Marshall, J., & Hallegraeff, G. (2001). No Title. In: Hallegraeff, G.M., Blackburn, S.I., Bolch, C.J., Lewis, R.J. (Eds.), Harmful Algal Blooms 2000. Intergovernmental Oceanographic Commission of UNESCO, Hobart, Tasmania, 54–57.
Penna, A., Garcés, E., Vila, M., Giacobbe, M. G., Fraga, S., Lugliè, A., Lugliè, A., Bravo, I., Bertozzini, & E. Vernesi, C. (2005). Alexandrium catenella (Dinophyceae), a toxic ribotype expanding in the NW Mediterranean Sea. Marine Biology, 148(1), 13–23.
https://doi.org/10.1007/s00227-005-0067-5
Praptiwi, R. A. (2014). Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima. (Robert Gordon University).
https://doi.org/10.1177/0266242610391936
Rains, L. K., & Parsons, M. L. (2015). Gambierdiscus species exhibit different epiphytic behaviors toward a variety of macroalgal hosts. Harmful Algae, 49, 29–39.
https://doi.org/10.1016/j.hal.2015.08.005
Reguera, B., Alonso, R., Moreira, Á., & Silvia, M. (2011). Guía para el diseño y puesta en marcha de un plan de seguimiento de microalgas productoras de toxinas. Manuales y Guías COI de UNESCO y OIEA, Paris y Viena. Manuales y Guías de La COI, 59, 1–49.
Stein, J. (1973). Handbook of Phycological Methods: Culture Methods and Growth Measurements (Cambridge).
Tarazona-Janampa, U. (2019). Effect of associated bacteria on growth and toxigenicity in cultured isolates of the dinoflagellate Prorocentrum lima from Mexico Effect of associated bacteria on growth and toxigenicity in cultured isolates of the dinoflagellate Prorocentrum lima from Me (Universidad Veracruzana, Mexico).
https://doi.org/htpps//:10.13140/RG.2.2.12826.90567
Tarazona-Janampa, U., Cembella, A., Pelayo-Zárate, M., Pajares, S., Márquez-Valdelamar, L., Okolodkov, Y., Tebben, J., Krock, B., & Durán-Riveroll, L. (2020). Associated Bacteria and Their Effects on Growth and Toxigenicity of the Dinoflagellate Prorocentrum lima Species Complex From Epibenthic Substrates Along Mexican Coasts. Frontiers in Marine Science |, 7(569), 1–18.
https://doi.org/10.3389/fmars.2020.00569
Tawong, W., Nishimura, T., Sakanari, H., Sato, S., Yamaguchi, H., & Adachi, M. (2014). Distribution and molecular phylogeny of the dinoflagellate genus Ostreopsis in Thailand. Harmful Algae, 37, 160–171. https://doi.org/10.1016/j.hal.2014.06.003
Tester, P. A., Kibler, S. R., Holland, W. C., Usup, G., Vandersea, M. W., Leaw, C. P., Mohammad-Noor, N., Faust, M., & Litaker, R. W. (2014). Sampling harmful benthic dinoflagellates: Comparison of artificial and natural substrate methods. Harmful Algae, 39, 8–25. https://doi.org/10.1016/j.hal.2014.06.009
Torgensen, T., Miles, C., Rundberget, T., & Wilkins, A. (2008). New Esters of Okadaic Acid in Seawater and Blue Mussels (Mytilus edulis). J. Agric. Food Chem, 56, 9628–9635.
Uchida, H., Watanabe, R., Matsushina, R., Uchida, N., Nagai, H., Kamio, M., Murata, M., Yasumoto, T., & Suzuki, T. (2014). A Convenient HPLC Method for Detection of Okadaic Acid Analogs as 9-Anthrylmethyl Esters with Automated Sample Cleanup by Column Switching. Journal of Aoac International, 97(2), 391–397. https://doi.org/10.5740/jaoacint.SGEUchida
Vale, P., Veloso, V., & Amorim, A. (2009). Toxin composition of a Prorocentrum lima strain isolated from the Portuguese coast. Toxicon, 54(2), 145–152. https://doi.org/10.1016/j.toxicon.2009.03.026
Vanucci, S., Guerrini, F., Milandri, A., & Pistocchi, R. (2010). Effects of different levels of N- and P-deficiency on cell yield , okadaic acid , DTX-1 , protein and carbohydrate dynamics in the benthic dinoflagellate Prorocentrum lima. Harmful Algae, 9(6), 590–599. https://doi.org/10.1016/j.hal.2010.04.009
Varkitzi, I., Hatzianestis, I., Pyrgaki, C., Pagou, K., Granelí, E., Pavlidou, A., Montesanto, B., & Economou-Amilli, A. (2010). Unbalanced N:P ratios and nutrient stress controlling growth and toxin production of the harmful
dinoflagellate Prorocentrum lima (Ehrenberg) Dodge. Harmful Algae, 9, 304–311. https://doi.org/10.1016/j.hal.2009.12.001
Águila-Ramírez, R., Arenas-González, A., Hernández-Guerrero, C., González-Acosta, B., Borges-Souza, J., Véron, B., & Hellio, C. (2012). Antimicrobial and antifouling activities achieved by extracts of seaweeds from Gulf of California, Mexico. Hidrobiologica, 22(1), 8–15.
Aligizaki, K., & Nikolaidis, G. (2006). The presence of the potentially toxic genera Ostreopsis and Coolia (Dinophyceae) in the North Aegean Sea, Greece. Harmful Algae, 5(6), 717–730
https://doi.org/10.1016/j.hal.2006.02.005
Aligizaki, K., & Nikolaidis, G. (2008). Morphological identification of two tropical dinoflagellates of the genera Gambierdiscus and Sinophysis in the Mediterranean Sea. Journal of Biological Research, 9, 75–82.
Aligizaki, K., Nikolaidis, G., Katikou, P., Baxevanis, A., & Abatzopoulos, T. (2009). Potentially toxic epiphytic Prorocentrum (Dinophyceae) species in Greek coastal waters. Harmful Algae, 8(2), 299–311.https://doi.org/10.1016/j.hal.2008.07.002
Aquino-Cruz, A., Purdie, D., & Morris, S. (2018). Effect of increasing sea water temperature on the growth and toxin production of the benthic dinoflagellate Prorocentrum lima. Hydrobiologia, 813(1), 103–122. https://doi.org/10.1007/s10750-018-3512-4
Arbeláez, N., Mancera-Pineda, J., & Reguera, B. (2020). Structural variation of potentially toxic epiphytic dinoflagellates on Thalassia testudinum from two coastal systems of Colombian Caribbean. Harmful Algae, 92(January), 101738. https://doi.org/10.1016/j.hal.2019.101738
Aumeerun, S., Soulange-Govinden, J., Driver, M., Rao, A., Ravishankar, G., & Neetoo, H. (2019). Macroalgae and Microalgae. In Handbook of Algal Technologies
and Phytochemicals (p. 207).
Berdalet, E., Fleming, L., Gowen, R., Davidson, K., Hess, P., Backer, L., Moore, S., Hoagland, P. & Enevoldsen, H. (2016). Marine harmful algal blooms, human health and wellbeing: challenges and opportunities in the 21st century. Journal of the Marine Biological Association of the United Kingdom, 96(1), 61–91. https://doi.org/https//: 10.1017/ S00253 15415001733
Bomber, J., & Aikman, K. (1989). The Ciguatera Dinoflagellates. Biological Oceanography, 6, 291–311.
Bomber, J., Guillard, R., & Nelson, W. (1988). Roles of temperature, salinity, and light in seasonality, growth, and toxicity of ciguatera-causing Gambierdiscus toxicus Adachi et Fukuyo (Dinophyceae). J. Exp. Mar. Biol. Ecol., 115, 53–65.
Bomber, J., Rubio, M., & Norris, D. (1989). Epiphytism of dinoflagellates associated with the disease ciguatera: substrate specificity and nutrition. Phycologia, 28(3), 360–368.
https://doi.org/10.2216/i0031-8884-28-3-360.1
Bravo, I., Fernández, M. L., Ramilo, I., & Martínez, A. (2001). Toxin composition of the toxic dinoflagellate Prorocentrum lima isolated from different locations along the Galician coast (NW Spain). Toxicon, 39(10), 1537–1545. https://doi.org/10.1016/S0041-0101(01)00126-X
Bravo, I., Rodríguez, F., Ramilo, I., & Afonso-Carrillo, J. (2020). Epibenthic Harmful Marine Dinoflagellates from Fuerteventura (Canary Islands), with Special Reference to the Ciguatoxin-Producing Gambierdiscus. J. Mar. Sci. Eng., 8, 0909.
Carlson, R., Morey-Gaines, G., Tindall, D., & Dickey, R. (1984). Ecology of Toxic Dinoflagellates from the Caribbean Sea Effects of Macroalgal Extracts on Growth in Culture. Sea Food Toxins, 24, 271–
https://doi.org/doi:10.1021/bk-1984-0262.ch024
Catuto-Magallan, R. (2019). Composición y abundancia de dinoflagelados epibentónicos asociados a macroalgas en dos playas de la Provincia de Santa Elena. Universidad Estatal Península de Santa Elena.
Chandia, P. (2020). Valor agregado a macroalgas chilenas de exportación: caracterización de ficocoloides, denominación de origen y diversificación comercial. Proyecto BBPP 18BPE-93853.
Chinain, M., Germain, M., Deparis, X., Pauillac, S., & Legrand, A. (1999). Seasonal abundance and toxicity of the dinoflagellate Gambierdiscus spp. (Dinophyceae), the causative agent of ciguatera in Tahiti, French Polynesia. Marine Biology, 135, 259–267. https://doi.org/doi: 10.1007/s002270050623
David, H., Laza-Martínez, A., Kromkamp, J. C., & Orive, E. (2018). Physiological response of Prorocentrum lima (Dinophyceae) to varying light intensities. FEMS Microbiology Ecology, 94(1), 1–12. https://doi.org/10.1093/femsec/fix166
Faust, M. (1995). Observation of sand-dwelling toxic dinoflagellates (Dinophyceae) from widely differing sites, incluiding two new species. Journal Phycol., 42, 154–159.
Faust, M. A. (1998). Mixotrophy in tropical benthic dinoflagellates. In: Reguera, B., Blanco, J. Fernandez, L., Wyatt, T. (Eds.) Harmful Algae. Xunta de Galicia and Intergovernmental Oceanographic Commission of UNESCO, Paris, Pp 390-393.
Faust, M., & Gulledge, R. (2004). Identifying Harmful Marine Dinoflagellates. Journal of Applied Phycology, 16(1), 79. https://doi.org/10.1023/b:japh.0000019147.40273.1b
Faust, M. A. (1991). Morphology of Ciguatera-causing Prorocentrum lima (Pyrrophyta) from widely differing sites. J. Phycol., 27, 642–648.
Foden, J., Purdie, D., Morris, S., & Nascimento, S. (2005). Epiphytic abundance and toxicity of Prorocentrum lima populations in the Fleet Lagoon, UK. Harmful Algae, 4, 1063–1074.
https://doi.org/https//:10.1016/j.hal.2005.03.004
Fukuyo, Y. (1981). Taxonomical Study on Benthic Dinoflagellates Collected in Coral Reefs. Bulletin of the Japanese Society of Scientific Fisheries, 47(8), 967–978.
GEOHAB. (2012). Global Ecology and Oceanography of Harmful Algal Blooms, GEOHAB Core Research Project: HABs in Benthic Systems. In A. Berdalet, E., Tester, P., Zingone (Ed.), Organization. IOC of UNESCO and SCOR, Paris and Newark.
Gu, S., Xiao, S., Zheng, J., Li, H., Liu, J., & Yang, W. (2019). ABC Transporters in Prorocentrum lima and Their Expression Under Different Environmental Conditions Including Okadaic Acid Production. Marine Drugs, 17(259), 1–16.
Guillard, R. R. L., & Hargraves, P. E. (1993). Stichochrysis immobilis is a diatom, not a chrysophyte. Phycologia, 32(3), 234–236. https://doi.org/10.2216/i0031-8884-32-3-234.1
Hachani, M. A., Dhib, A., Fathalli, A., Ziadi, B., Turki, S., & Aleya, L. (2018). Harmful epiphytic dinoflagellate assemblages on macrophytes in the Gulf of Tunis. Harmful Algae, 77(June), 29–42.
https://doi.org/10.1016/j.hal.2018.06.006
Hales, S., Weinstein, P., & Woodward, A. (1999). Ciguatera (Fish Poisoning), El Niño, and Pacific Sea Surface Temperatures. Ecosystem Health, 5, 20–25.
https://doi.org/doi: 10.1046/j.1526-0992. 1999. 0990 3.x
Heredia-Tapia, A., Arredondo-Vega, B., Nuñez-Vázquez, E., Yasumoto, T., Yasuda, M., & Ochoa, J. (2002). Isolation of Prorocentrum lima (Syn. Exuviella lima) and diarrhetic shellfish poisoning (DSP) risk assessment in the Gulf of California, Mexico. Toxicon 4, 40, 1121–1127.
Hou, D., Liang, J., Zou, C., Li, H., Liu, J., & Yang, W. (2015). MRP functional activity and character in the dinoflagellate Prorocentrum lima. Journal of Applied Phycology, 28, 1667–1676.
https://doi.org/https//:10.1007/s10811-015-0679-1
Hu, Tingmo, LeBlanc, P., Burton, I. W., Walter, J. A., McCarron, P., Melanson, J. E., Strangman, W., & Wright, J. L. C. (2017). Sulfated diesters of okadaic acid and DTX-1: Self-protective precursors of diarrhetic shellfish poisoning (DSP) toxins. Harmful Algae, 63, 85–93. https://doi.org/10.1016/j.hal.2017.01.012
Hu, W., Xu, J., Sinkkonen, J., & Wu, J. (2010). Polyketides from Marine Dinoflagellates of the Genus Prorocentrum, Biosynthetic Origin and Bioactivity of Their Okadaic Acid Analogues. Mini-Reviews in Medicinal Chemistry, 10, 51–61.
https://doi.org/10.2174/138955710791112541
Irola-Sansores, E. D., Delgado-Pech, B., García-Mendoza, E., Núñez-Vázquez, E. J., Olivos-Ortiz, A., & Almazán-Becerril, A. (2018). Population dynamics of benthic-epiphytic dinoflagellates on two macroalgae from coral reef systems of the northern Mexican Caribbean. Frontiers in Marine Science, 5, 1–14.
https://doi.org/10.3389/fmars.2018.00487
Karafas, S., York, R., & Tomas, C. (2015). Morphological and genetic analysis of the Coolia monotis species complex with the introduction of two new species, Coolia santacroce sp. nov. and Coolia palmyrensis sp. nov. (Dinophyceae). Harmful Algae, 46, 18–33.
https://doi.org/10.1016/j.hal.2015.05.002
Kibler, S. R., Tester, P. A., Kunkel, K. E., Moore, S. K., & Litaker, R. W. (2015). Effects of ocean warming on growth and distribution of dinoflagellates associated with ciguatera fish poisoning in the Caribbean. Ecological Modelling, 316, 194–210.
https://doi.org/10.1016/j.ecolmodel.2015.08.020
Lartigue, J., Jester, E. L. E., Dickey, R. W., & Villareal, T. A. (2009). Nitrogen source effects on the growth and toxicity of two strains of the ciguatera-causing dinoflagellate Gambierdiscus toxicus. Harmful Algae, 8, 781–791. https://doi.org/10.1016/j.hal.2008.05.006
Lassus, P., Chomerat, N., Hess, P., & Nezan, E. (2016). Microalgues toxiques et nuisibles de l’océan mondial. COI Manuels et Guides, 68 / Toxic and Harmful Microalgae of the World Ocean. IOC Manuals and Guides, 68.
Laza-Martinez, A., Orive, E., & Miguel, I. (2011). Morphological and genetic characterization of benthic dinoflagellates of the genera Coolia, Ostreopsis and Prorocentrum from the south-eastern Bay of Biscay. European Journal of Phycology, 46(1), 45–65.
https://doi.org/10.1080/09670262.2010.550387
Lee, S., Hwang, B., Kim, H., Yih, W., & Jeong, E. (2015). A New Diol Ester Derivative of Dinophysistoxin-1 from Cultures of Prorocentrum lima Collected in South Korea. Bulletin of the Korean Chemical Society, 395–398. https://doi.org/10.1002/bkcs.10031
LeGresley, M., & McDermott, G. (2010). Counting chamber methods for quantitative phytoplankton analysis - haemocytometer, Palmer-Maloney cell and Sedgewick-Rafter cell. In Microscopic and molecular methods for Quantitative phytoplankton analysis, 25–30.
Levasseur, M., Thompson, P., & Harrison, P. (1993). Physiological acclimation of marine phytoplankton to different nitrogen sources. J. Phycol., 29, 587–595.
Lewis, N., Wolny, J., Achenbach, J., Ellis, L., Pitula, J., Rafuse, C., Rosales, D. & McCarron, P. (2018). Identification, growth and toxicity assessment of Coolia meunier (Dinophyceae) from Nova Scotia, Canada. Harmful Algae, 75, 45–56.
https://doi.org/10.1016/j.hal.2018.04.001
Litaker, R. W., Vandersea, M. W., Faust, M. A., Kibler, S. R., Nau, A. W., Holland, W. C., Chinain, M., Holmes, M., & Tester, P. A. (2010). Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus. Toxicon, 56(5), 711–730.
https://doi.org/10.1016/j.toxicon.2010.05.017
Lobel, P., Anderson, D., & Durand-Clement, M. (1988). Assessment of Ciguatera Dinoflagellate Populations: Sample Variability and Algal Substrate Selection. The Biological Bulletin, 175(1), 94–101. https://doi.org/10.2307/1541896
López-Rosales, L., Gallardo-Rodríguez, J. J., Sánchez-Mirón, A., Cerón-García, M. del C., Belarbi, E. H., García-Camacho, F., & Molina-Grima, E. (2013). Simultaneous effect of temperature and irradiance on growth and okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum. Toxins, 6(1), 229–253.
https://doi.org/10.3390/toxins6010229
Mangialajo, L., Ganzin, N., Accoroni, S., Asnaghi, V., Blanfuné, A., Cabrini, M., Chavanon, F., Chiantore, M., Cohu, S., Costa, E., Fornasaro, D., Grossel, H., Marco-Miralles, F., Masó, M., Reñé, A., Rossi, A., Sala, M., Thibaut, T., Totti, C., Vila, M., & Lemée, R. (2011). Trends in Ostreopsis proliferation along the Northern Mediterranean coasts. Toxicon, 57(3), 408–420.
https://doi.org/10.1016/j.toxicon.2010.11.019
Marr, J., Hu, T., Pleasance, S., Quilliam, M., & Wright, J. (1992). Detection of new 7-O-acyl derivatives of diarrhetic shellfish poisoning toxins by liquid chromatography-mass spectrometry. Toxicon, 30(12), 1621–1630.
Matsuhiro, B., & Urzúa, C. (1990). Agars from Gracilaria chilensis (Gracilariales). Journal of Applied Phycology, 2(3), 273–279. https://doi.org/https//:10.1007/BF02179785
McLachlan, J. L., Marr, J. C., Conlon?Keily, A., & Adamson, A. (1994). Effects of nitrogen concentration and cold temperature on DSP?toxin concentrations in the dinoflagellate Prorocentrum lima (prorocentrales, dinophyceae). Natural Toxins, 2(5), 263–270.
https://doi.org/10.1002/nt.2620020504
Moreira-González, A. R., Fernandes, L. F., Uchida, H., Uesugi, A., Suzuki, T., Chomérat, N., Bilien, G., & Mafra, L. L. (2018). Variations in morphology, growth, and toxicity among strains of the Prorocentrum lima species complex isolated from Cuba and Brazil. Journal of Applied Phycology, 31(1), 519–532.
https://doi.org/10.1007/s10811-018-1587-y
Morton, S., & Faust, M. (1997). Survey of Toxic Epiphytic Dinoflagellates from the Belizean Barrier Reef Ecosystem. Bulletin of Marine Science -Miami, 61(3), 899–906.
Morton, S., Norris, D., & Bomber, J. (1992). Effect of temperature, salinity and light intensity on the growth and seasonality of toxic dinoflagellates associated with ciguatera. Journal of Experimental Marine Biology and Ecology, 157, 79–90.
https://doi.org/10.1016/0022-0981(92)90076-M
Murakami, Y., Oshima, Y., & Yasumoto, T. (1982). Identification of Okadaic Acid As a Toxic Component of a Marine Dinoflagellate Prorocentrum lima. Nippon Suisan Gakkaishi, 48(1), 69–72. https://doi.org/https//:10.2331/suisan.48.69
Nagahama, Y., Murray, S., Tomaru, A., & Fukuyo, Y. (2011). Species boundaries in the toxic dinoflagellate Prorocentrum lima (Dinophyceae, Prorocentrales), based on morphological and phylogenetic characters. Journal of Phycology, 47(1), 178–189.
https://doi.org/10.1111/j.1529-8817.2010.00939.x
Nakahara, H., Sakami, T., Chinain, M., & Ishida, Y. (1996). The role of macroalgae in epiphytism of the toxic dinoflagellate Gambierdiscus toxicus (Dinophyceae). Phycological Research, 44(2), 113–117. https://doi.org/10.1111/j.1440-1835.1996.tb00385.x
Nascimento, S. M., Purdie, D. A., & Morris, S. (2005). Morphology, toxin composition and pigment content of Prorocentrum lima strains isolated from a coastal lagoon in southern UK. Toxicon, 45(5), 633–649. https://doi.org/10.1016/j.toxicon.2004.12.023
Nascimento, S. M., Salgueiro, F., Menezes, M., Oliveira, F. de A., Magalhães, V. C. P., De Paula, J. C., & Morris, S. (2016). Prorocentrum lima from the South Atlantic: Morphological, molecular and toxicological characterization. Harmful Algae, 57, 39–48.
https://doi.org/10.1016/j.hal.2016.05.006
Nishimura, T., Uchida, H., Noguchi, R., Oikawa, H., Suzuki, T., Funaki, H., hara, C., Hagino, K., Arimitsu, S., Tanii, Y., Abe, S., Hashimoto, K., Mimura, K., Tanaka, K., Yanagida., & I. Adachi, M. (2020). Abundance of the benthic dinoflagellate Prorocentrum and the diversity, distribution, and diarrhetic shellfish toxin production of Prorocentrum lima complex and P. caipirignum in Japan. Harmful Algae, 96, 101687. https://doi.org/10.1016/j.hal.2019.101687
Okolodrov, Y., Merino-Virgilio, F., Aké-Castillo, J., Aguilar-Trujillo, A., Espinoza-Matías, S., & Herrera-Silveira, J. (2014). Seasonal changes in epiphytic dinoflallelate assemblages near the Northern coast ot the Yucatan peninsula, Gulf of Mexico. Acta Botanica Mexicana, 107, 121–151.
Parsons, M., & Preskitt, L. (2007). A survey of epiphytic dinoflagellates from the coastal waters of the island of Hawai’i. Harmful Algae, 6(5), 658–669. https://doi.org/10.1016/j.hal.2007.01.001
Parsons, M., Settlemier, C., & Ballauer, J. (2011). An examination of the epiphytic nature of Gambierdiscus toxicus, a dinoflagellate involved in ciguatera fish poisoning. Harmful Algae, 10(6), 598–605. https://doi.org/10.1016/j.hal.2011.04.011
Paz, B., Vázquez, J., Riobó, P., & Franco, J. (2006). Study of the effect of temperature, irradiance and salinity on growth and yessotoxin production by the dinoflagellate Protoceratium reticulatum in culture by using a kinetic and factorial approach. Marine Environmental Research, 62(4), 286–300.
https://doi.org/10.1016/j.marenvres.2006.04.066
Pearce, I., Marshall, J., & Hallegraeff, G. (2001). No Title. In: Hallegraeff, G.M., Blackburn, S.I., Bolch, C.J., Lewis, R.J. (Eds.), Harmful Algal Blooms 2000. Intergovernmental Oceanographic Commission of UNESCO, Hobart, Tasmania, 54–57.
Penna, A., Garcés, E., Vila, M., Giacobbe, M. G., Fraga, S., Lugliè, A., Lugliè, A., Bravo, I., Bertozzini, & E. Vernesi, C. (2005). Alexandrium catenella (Dinophyceae), a toxic ribotype expanding in the NW Mediterranean Sea. Marine Biology, 148(1), 13–23.
https://doi.org/10.1007/s00227-005-0067-5
Praptiwi, R. A. (2014). Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima. (Robert Gordon University).
https://doi.org/10.1177/0266242610391936
Rains, L. K., & Parsons, M. L. (2015). Gambierdiscus species exhibit different epiphytic behaviors toward a variety of macroalgal hosts. Harmful Algae, 49, 29–39.
https://doi.org/10.1016/j.hal.2015.08.005
Reguera, B., Alonso, R., Moreira, Á., & Silvia, M. (2011). Guía para el diseño y puesta en marcha de un plan de seguimiento de microalgas productoras de toxinas. Manuales y Guías COI de UNESCO y OIEA, Paris y Viena. Manuales y Guías de La COI, 59, 1–49.
Stein, J. (1973). Handbook of Phycological Methods: Culture Methods and Growth Measurements (Cambridge).
Tarazona-Janampa, U. (2019). Effect of associated bacteria on growth and toxigenicity in cultured isolates of the dinoflagellate Prorocentrum lima from Mexico Effect of associated bacteria on growth and toxigenicity in cultured isolates of the dinoflagellate Prorocentrum lima from Me (Universidad Veracruzana, Mexico).
https://doi.org/htpps//:10.13140/RG.2.2.12826.90567
Tarazona-Janampa, U., Cembella, A., Pelayo-Zárate, M., Pajares, S., Márquez-Valdelamar, L., Okolodkov, Y., Tebben, J., Krock, B., & Durán-Riveroll, L. (2020). Associated Bacteria and Their Effects on Growth and Toxigenicity of the Dinoflagellate Prorocentrum lima Species Complex From Epibenthic Substrates Along Mexican Coasts. Frontiers in Marine Science |, 7(569), 1–18.
https://doi.org/10.3389/fmars.2020.00569
Tawong, W., Nishimura, T., Sakanari, H., Sato, S., Yamaguchi, H., & Adachi, M. (2014). Distribution and molecular phylogeny of the dinoflagellate genus Ostreopsis in Thailand. Harmful Algae, 37, 160–171. https://doi.org/10.1016/j.hal.2014.06.003
Tester, P. A., Kibler, S. R., Holland, W. C., Usup, G., Vandersea, M. W., Leaw, C. P., Mohammad-Noor, N., Faust, M., & Litaker, R. W. (2014). Sampling harmful benthic dinoflagellates: Comparison of artificial and natural substrate methods. Harmful Algae, 39, 8–25. https://doi.org/10.1016/j.hal.2014.06.009
Torgensen, T., Miles, C., Rundberget, T., & Wilkins, A. (2008). New Esters of Okadaic Acid in Seawater and Blue Mussels (Mytilus edulis). J. Agric. Food Chem, 56, 9628–9635.
Uchida, H., Watanabe, R., Matsushina, R., Uchida, N., Nagai, H., Kamio, M., Murata, M., Yasumoto, T., & Suzuki, T. (2014). A Convenient HPLC Method for Detection of Okadaic Acid Analogs as 9-Anthrylmethyl Esters with Automated Sample Cleanup by Column Switching. Journal of Aoac International, 97(2), 391–397. https://doi.org/10.5740/jaoacint.SGEUchida
Vale, P., Veloso, V., & Amorim, A. (2009). Toxin composition of a Prorocentrum lima strain isolated from the Portuguese coast. Toxicon, 54(2), 145–152. https://doi.org/10.1016/j.toxicon.2009.03.026
Vanucci, S., Guerrini, F., Milandri, A., & Pistocchi, R. (2010). Effects of different levels of N- and P-deficiency on cell yield , okadaic acid , DTX-1 , protein and carbohydrate dynamics in the benthic dinoflagellate Prorocentrum lima. Harmful Algae, 9(6), 590–599. https://doi.org/10.1016/j.hal.2010.04.009
Varkitzi, I., Hatzianestis, I., Pyrgaki, C., Pagou, K., Granelí, E., Pavlidou, A., Montesanto, B., & Economou-Amilli, A. (2010). Unbalanced N:P ratios and nutrient stress controlling growth and toxin production of the harmful
dinoflagellate Prorocentrum lima (Ehrenberg) Dodge. Harmful Algae, 9, 304–311. https://doi.org/10.1016/j.hal.2009.12.001
Varkitzi, I., Pagou, K., Pyrgaki, C., & Hatzianestis, I. (2017). A Biomass Upscale System for the Marine Dinoflagellate Prorocentrum lima and the Production of Bioactive Lipophilic Toxins. International Journal of Applied Sciences and Biotechnology, 5(4), 479–485. https://doi.org/10.3126/ijasbt.v5i4.18561
Wang, L., Wang, X., Wu, H., & Liu, R. (2014). Overview on biological activities and molecular characteristics of sulfated polysaccharides from marine green algae in recent years. In Marine Drugs (Vol. 12). https://doi.org/10.3390/md12094984
Wang, S., Chen, J., Li, Z., Wang, Y., Fu, B., Han, X., & Zheng, L. (2015). Cultivation of the benthic microalga Prorocentrum lima for the production of diarrhetic shellfish poisoning toxins in a vertical flat photobioreactor. Bioresource Technology, 179, 243–248. https://doi.org/https//:10.1016/j.biortech.2014.12.019
Wu, H., Chen, J., Peng, J., Zhong, Y., Guo, M., Tan, Z., Tan, Z., Zhai, Y., & Lu, S. (2020). Nontarget screening and toxicity evaluation of diol esters of okadaic acid and dinophysistoxins reveal intraspecies difference of Prorocentrum lima. Environmental Science & Technology, 1–40. https://doi.org/10.1021/acs.est.0c03691
Yang, A., Lee, S., Du Yoo, Y., Seop Kim, H., Ju Jeong, E., & Rho, J. (2017). Limaol: A Polyketide from the Benthic Marine Dinoflagellate Prorocentrum lima. Journal of Natural Products, 80, 1688–1692. https://doi.org/10.1021/acs.jnatprod.7b00127

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[1] Águila-Ramírez, R., Arenas-González, A., Hernández-Guerrero, C., González-Acosta, B., Borges-Souza, J., Véron, B., & Hellio, C. (2012). Antimicrobial and antifouling activities achieved by extracts of seaweeds from Gulf of California, Mexico. Hidrobiologica, 22(1), 8–15.

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[3] https://doi.org/10.1016/j.hal.2006.02.005

[4] Aligizaki, K., & Nikolaidis, G. (2008). Morphological identification of two tropical dinoflagellates of the genera Gambierdiscus and Sinophysis in the Mediterranean Sea. Journal of Biological Research, 9, 75–82.

[5] Aligizaki, K., Nikolaidis, G., Katikou, P., Baxevanis, A., & Abatzopoulos, T. (2009). Potentially toxic epiphytic Prorocentrum (Dinophyceae) species in Greek coastal waters. Harmful Algae, 8(2), 299–311.https://doi.org/10.1016/j.hal.2008.07.002

[6] Aquino-Cruz, A., Purdie, D., & Morris, S. (2018). Effect of increasing sea water temperature on the growth and toxin production of the benthic dinoflagellate Prorocentrum lima. Hydrobiologia, 813(1), 103–122. https://doi.org/10.1007/s10750-018-3512-4

[7] Arbeláez, N., Mancera-Pineda, J., & Reguera, B. (2020). Structural variation of potentially toxic epiphytic dinoflagellates on Thalassia testudinum from two coastal systems of Colombian Caribbean. Harmful Algae, 92(January), 101738. https://doi.org/10.1016/j.hal.2019.101738

[8] Aumeerun, S., Soulange-Govinden, J., Driver, M., Rao, A., Ravishankar, G., & Neetoo, H. (2019). Macroalgae and Microalgae. In Handbook of Algal Technologies

[9] and Phytochemicals (p. 207).

[10] Berdalet, E., Fleming, L., Gowen, R., Davidson, K., Hess, P., Backer, L., Moore, S., Hoagland, P. & Enevoldsen, H. (2016). Marine harmful algal blooms, human health and wellbeing: challenges and opportunities in the 21st century. Journal of the Marine Biological Association of the United Kingdom, 96(1), 61–91. https://doi.org/https//: 10.1017/ S00253 15415001733

[11] Bomber, J., & Aikman, K. (1989). The Ciguatera Dinoflagellates. Biological Oceanography, 6, 291–311.

[12] Bomber, J., Guillard, R., & Nelson, W. (1988). Roles of temperature, salinity, and light in seasonality, growth, and toxicity of ciguatera-causing Gambierdiscus toxicus Adachi et Fukuyo (Dinophyceae). J. Exp. Mar. Biol. Ecol., 115, 53–65.

[13] Bomber, J., Rubio, M., & Norris, D. (1989). Epiphytism of dinoflagellates associated with the disease ciguatera: substrate specificity and nutrition. Phycologia, 28(3), 360–368.

[14] https://doi.org/10.2216/i0031-8884-28-3-360.1

[15] Bravo, I., Fernández, M. L., Ramilo, I., & Martínez, A. (2001). Toxin composition of the toxic dinoflagellate Prorocentrum lima isolated from different locations along the Galician coast (NW Spain). Toxicon, 39(10), 1537–1545. https://doi.org/10.1016/S0041-0101(01)00126-X

[16] Bravo, I., Rodríguez, F., Ramilo, I., & Afonso-Carrillo, J. (2020). Epibenthic Harmful Marine Dinoflagellates from Fuerteventura (Canary Islands), with Special Reference to the Ciguatoxin-Producing Gambierdiscus. J. Mar. Sci. Eng., 8, 0909.

[17] Carlson, R., Morey-Gaines, G., Tindall, D., & Dickey, R. (1984). Ecology of Toxic Dinoflagellates from the Caribbean Sea Effects of Macroalgal Extracts on Growth in Culture. Sea Food Toxins, 24, 271–

[18] https://doi.org/doi:10.1021/bk-1984-0262.ch024

[19] Catuto-Magallan, R. (2019). Composición y abundancia de dinoflagelados epibentónicos asociados a macroalgas en dos playas de la Provincia de Santa Elena. Universidad Estatal Península de Santa Elena.

[20] Chandia, P. (2020). Valor agregado a macroalgas chilenas de exportación: caracterización de ficocoloides, denominación de origen y diversificación comercial. Proyecto BBPP 18BPE-93853.

[21] Chinain, M., Germain, M., Deparis, X., Pauillac, S., & Legrand, A. (1999). Seasonal abundance and toxicity of the dinoflagellate Gambierdiscus spp. (Dinophyceae), the causative agent of ciguatera in Tahiti, French Polynesia. Marine Biology, 135, 259–267. https://doi.org/doi: 10.1007/s002270050623

[22] David, H., Laza-Martínez, A., Kromkamp, J. C., & Orive, E. (2018). Physiological response of Prorocentrum lima (Dinophyceae) to varying light intensities. FEMS Microbiology Ecology, 94(1), 1–12. https://doi.org/10.1093/femsec/fix166

[23] Faust, M. (1995). Observation of sand-dwelling toxic dinoflagellates (Dinophyceae) from widely differing sites, incluiding two new species. Journal Phycol., 42, 154–159.

[24] Faust, M. A. (1998). Mixotrophy in tropical benthic dinoflagellates. In: Reguera, B., Blanco, J. Fernandez, L., Wyatt, T. (Eds.) Harmful Algae. Xunta de Galicia and Intergovernmental Oceanographic Commission of UNESCO, Paris, Pp 390-393.

[25] Faust, M., & Gulledge, R. (2004). Identifying Harmful Marine Dinoflagellates. Journal of Applied Phycology, 16(1), 79. https://doi.org/10.1023/b:japh.0000019147.40273.1b

[26] Faust, M. A. (1991). Morphology of Ciguatera-causing Prorocentrum lima (Pyrrophyta) from widely differing sites. J. Phycol., 27, 642–648.

[27] Foden, J., Purdie, D., Morris, S., & Nascimento, S. (2005). Epiphytic abundance and toxicity of Prorocentrum lima populations in the Fleet Lagoon, UK. Harmful Algae, 4, 1063–1074.

[28] https://doi.org/https//:10.1016/j.hal.2005.03.004

[29] Fukuyo, Y. (1981). Taxonomical Study on Benthic Dinoflagellates Collected in Coral Reefs. Bulletin of the Japanese Society of Scientific Fisheries, 47(8), 967–978.

[30] GEOHAB. (2012). Global Ecology and Oceanography of Harmful Algal Blooms, GEOHAB Core Research Project: HABs in Benthic Systems. In A. Berdalet, E., Tester, P., Zingone (Ed.), Organization. IOC of UNESCO and SCOR, Paris and Newark.

[31] Gu, S., Xiao, S., Zheng, J., Li, H., Liu, J., & Yang, W. (2019). ABC Transporters in Prorocentrum lima and Their Expression Under Different Environmental Conditions Including Okadaic Acid Production. Marine Drugs, 17(259), 1–16.

[32] Guillard, R. R. L., & Hargraves, P. E. (1993). Stichochrysis immobilis is a diatom, not a chrysophyte. Phycologia, 32(3), 234–236. https://doi.org/10.2216/i0031-8884-32-3-234.1

[33] Hachani, M. A., Dhib, A., Fathalli, A., Ziadi, B., Turki, S., & Aleya, L. (2018). Harmful epiphytic dinoflagellate assemblages on macrophytes in the Gulf of Tunis. Harmful Algae, 77(June), 29–42.

[34] https://doi.org/10.1016/j.hal.2018.06.006

[35] Hales, S., Weinstein, P., & Woodward, A. (1999). Ciguatera (Fish Poisoning), El Niño, and Pacific Sea Surface Temperatures. Ecosystem Health, 5, 20–25.

[36] https://doi.org/doi: 10.1046/j.1526-0992. 1999. 0990 3.x

[37] Heredia-Tapia, A., Arredondo-Vega, B., Nuñez-Vázquez, E., Yasumoto, T., Yasuda, M., & Ochoa, J. (2002). Isolation of Prorocentrum lima (Syn. Exuviella lima) and diarrhetic shellfish poisoning (DSP) risk assessment in the Gulf of California, Mexico. Toxicon 4, 40, 1121–1127.

[38] Hou, D., Liang, J., Zou, C., Li, H., Liu, J., & Yang, W. (2015). MRP functional activity and character in the dinoflagellate Prorocentrum lima. Journal of Applied Phycology, 28, 1667–1676.

[39] https://doi.org/https//:10.1007/s10811-015-0679-1

[40] Hu, Tingmo, LeBlanc, P., Burton, I. W., Walter, J. A., McCarron, P., Melanson, J. E., Strangman, W., & Wright, J. L. C. (2017). Sulfated diesters of okadaic acid and DTX-1: Self-protective precursors of diarrhetic shellfish poisoning (DSP) toxins. Harmful Algae, 63, 85–93. https://doi.org/10.1016/j.hal.2017.01.012

[41] Hu, W., Xu, J., Sinkkonen, J., & Wu, J. (2010). Polyketides from Marine Dinoflagellates of the Genus Prorocentrum, Biosynthetic Origin and Bioactivity of Their Okadaic Acid Analogues. Mini-Reviews in Medicinal Chemistry, 10, 51–61.

[42] https://doi.org/10.2174/138955710791112541

[43] Irola-Sansores, E. D., Delgado-Pech, B., García-Mendoza, E., Núñez-Vázquez, E. J., Olivos-Ortiz, A., & Almazán-Becerril, A. (2018). Population dynamics of benthic-epiphytic dinoflagellates on two macroalgae from coral reef systems of the northern Mexican Caribbean. Frontiers in Marine Science, 5, 1–14.

[44] https://doi.org/10.3389/fmars.2018.00487

[45] Karafas, S., York, R., & Tomas, C. (2015). Morphological and genetic analysis of the Coolia monotis species complex with the introduction of two new species, Coolia santacroce sp. nov. and Coolia palmyrensis sp. nov. (Dinophyceae). Harmful Algae, 46, 18–33.

[46] https://doi.org/10.1016/j.hal.2015.05.002

[47] Kibler, S. R., Tester, P. A., Kunkel, K. E., Moore, S. K., & Litaker, R. W. (2015). Effects of ocean warming on growth and distribution of dinoflagellates associated with ciguatera fish poisoning in the Caribbean. Ecological Modelling, 316, 194–210.

[48] https://doi.org/10.1016/j.ecolmodel.2015.08.020

[49] Lartigue, J., Jester, E. L. E., Dickey, R. W., & Villareal, T. A. (2009). Nitrogen source effects on the growth and toxicity of two strains of the ciguatera-causing dinoflagellate Gambierdiscus toxicus. Harmful Algae, 8, 781–791. https://doi.org/10.1016/j.hal.2008.05.006

[50] Lassus, P., Chomerat, N., Hess, P., & Nezan, E. (2016). Microalgues toxiques et nuisibles de l’océan mondial. COI Manuels et Guides, 68 / Toxic and Harmful Microalgae of the World Ocean. IOC Manuals and Guides, 68.

[51] Laza-Martinez, A., Orive, E., & Miguel, I. (2011). Morphological and genetic characterization of benthic dinoflagellates of the genera Coolia, Ostreopsis and Prorocentrum from the south-eastern Bay of Biscay. European Journal of Phycology, 46(1), 45–65.

[52] https://doi.org/10.1080/09670262.2010.550387

[53] Lee, S., Hwang, B., Kim, H., Yih, W., & Jeong, E. (2015). A New Diol Ester Derivative of Dinophysistoxin-1 from Cultures of Prorocentrum lima Collected in South Korea. Bulletin of the Korean Chemical Society, 395–398. https://doi.org/10.1002/bkcs.10031

[54] LeGresley, M., & McDermott, G. (2010). Counting chamber methods for quantitative phytoplankton analysis - haemocytometer, Palmer-Maloney cell and Sedgewick-Rafter cell. In Microscopic and molecular methods for Quantitative phytoplankton analysis, 25–30.

[55] Levasseur, M., Thompson, P., & Harrison, P. (1993). Physiological acclimation of marine phytoplankton to different nitrogen sources. J. Phycol., 29, 587–595.

[56] Lewis, N., Wolny, J., Achenbach, J., Ellis, L., Pitula, J., Rafuse, C., Rosales, D. & McCarron, P. (2018). Identification, growth and toxicity assessment of Coolia meunier (Dinophyceae) from Nova Scotia, Canada. Harmful Algae, 75, 45–56.

[57] https://doi.org/10.1016/j.hal.2018.04.001

[58] Litaker, R. W., Vandersea, M. W., Faust, M. A., Kibler, S. R., Nau, A. W., Holland, W. C., Chinain, M., Holmes, M., & Tester, P. A. (2010). Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus. Toxicon, 56(5), 711–730.

[59] https://doi.org/10.1016/j.toxicon.2010.05.017

[60] Lobel, P., Anderson, D., & Durand-Clement, M. (1988). Assessment of Ciguatera Dinoflagellate Populations: Sample Variability and Algal Substrate Selection. The Biological Bulletin, 175(1), 94–101. https://doi.org/10.2307/1541896

[61] López-Rosales, L., Gallardo-Rodríguez, J. J., Sánchez-Mirón, A., Cerón-García, M. del C., Belarbi, E. H., García-Camacho, F., & Molina-Grima, E. (2013). Simultaneous effect of temperature and irradiance on growth and okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum. Toxins, 6(1), 229–253.

[62] https://doi.org/10.3390/toxins6010229

[63] Mangialajo, L., Ganzin, N., Accoroni, S., Asnaghi, V., Blanfuné, A., Cabrini, M., Chavanon, F., Chiantore, M., Cohu, S., Costa, E., Fornasaro, D., Grossel, H., Marco-Miralles, F., Masó, M., Reñé, A., Rossi, A., Sala, M., Thibaut, T., Totti, C., Vila, M., & Lemée, R. (2011). Trends in Ostreopsis proliferation along the Northern Mediterranean coasts. Toxicon, 57(3), 408–420.

[64] https://doi.org/10.1016/j.toxicon.2010.11.019

[65] Marr, J., Hu, T., Pleasance, S., Quilliam, M., & Wright, J. (1992). Detection of new 7-O-acyl derivatives of diarrhetic shellfish poisoning toxins by liquid chromatography-mass spectrometry. Toxicon, 30(12), 1621–1630.

[66] Matsuhiro, B., & Urzúa, C. (1990). Agars from Gracilaria chilensis (Gracilariales). Journal of Applied Phycology, 2(3), 273–279. https://doi.org/https//:10.1007/BF02179785

[67] McLachlan, J. L., Marr, J. C., Conlon?Keily, A., & Adamson, A. (1994). Effects of nitrogen concentration and cold temperature on DSP?toxin concentrations in the dinoflagellate Prorocentrum lima (prorocentrales, dinophyceae). Natural Toxins, 2(5), 263–270.

[68] https://doi.org/10.1002/nt.2620020504

[69] Moreira-González, A. R., Fernandes, L. F., Uchida, H., Uesugi, A., Suzuki, T., Chomérat, N., Bilien, G., & Mafra, L. L. (2018). Variations in morphology, growth, and toxicity among strains of the Prorocentrum lima species complex isolated from Cuba and Brazil. Journal of Applied Phycology, 31(1), 519–532.

[70] https://doi.org/10.1007/s10811-018-1587-y

[71] Morton, S., & Faust, M. (1997). Survey of Toxic Epiphytic Dinoflagellates from the Belizean Barrier Reef Ecosystem. Bulletin of Marine Science -Miami, 61(3), 899–906.

[72] Morton, S., Norris, D., & Bomber, J. (1992). Effect of temperature, salinity and light intensity on the growth and seasonality of toxic dinoflagellates associated with ciguatera. Journal of Experimental Marine Biology and Ecology, 157, 79–90.

[73] https://doi.org/10.1016/0022-0981(92)90076-M

[74] Murakami, Y., Oshima, Y., & Yasumoto, T. (1982). Identification of Okadaic Acid As a Toxic Component of a Marine Dinoflagellate Prorocentrum lima. Nippon Suisan Gakkaishi, 48(1), 69–72. https://doi.org/https//:10.2331/suisan.48.69

[75] Nagahama, Y., Murray, S., Tomaru, A., & Fukuyo, Y. (2011). Species boundaries in the toxic dinoflagellate Prorocentrum lima (Dinophyceae, Prorocentrales), based on morphological and phylogenetic characters. Journal of Phycology, 47(1), 178–189.

[76] https://doi.org/10.1111/j.1529-8817.2010.00939.x

[77] Nakahara, H., Sakami, T., Chinain, M., & Ishida, Y. (1996). The role of macroalgae in epiphytism of the toxic dinoflagellate Gambierdiscus toxicus (Dinophyceae). Phycological Research, 44(2), 113–117. https://doi.org/10.1111/j.1440-1835.1996.tb00385.x

[78] Nascimento, S. M., Purdie, D. A., & Morris, S. (2005). Morphology, toxin composition and pigment content of Prorocentrum lima strains isolated from a coastal lagoon in southern UK. Toxicon, 45(5), 633–649. https://doi.org/10.1016/j.toxicon.2004.12.023

[79] Nascimento, S. M., Salgueiro, F., Menezes, M., Oliveira, F. de A., Magalhães, V. C. P., De Paula, J. C., & Morris, S. (2016). Prorocentrum lima from the South Atlantic: Morphological, molecular and toxicological characterization. Harmful Algae, 57, 39–48.

[80] https://doi.org/10.1016/j.hal.2016.05.006

[81] Nishimura, T., Uchida, H., Noguchi, R., Oikawa, H., Suzuki, T., Funaki, H., hara, C., Hagino, K., Arimitsu, S., Tanii, Y., Abe, S., Hashimoto, K., Mimura, K., Tanaka, K., Yanagida., & I. Adachi, M. (2020). Abundance of the benthic dinoflagellate Prorocentrum and the diversity, distribution, and diarrhetic shellfish toxin production of Prorocentrum lima complex and P. caipirignum in Japan. Harmful Algae, 96, 101687. https://doi.org/10.1016/j.hal.2019.101687

[82] Okolodrov, Y., Merino-Virgilio, F., Aké-Castillo, J., Aguilar-Trujillo, A., Espinoza-Matías, S., & Herrera-Silveira, J. (2014). Seasonal changes in epiphytic dinoflallelate assemblages near the Northern coast ot the Yucatan peninsula, Gulf of Mexico. Acta Botanica Mexicana, 107, 121–151.

[83] Parsons, M., & Preskitt, L. (2007). A survey of epiphytic dinoflagellates from the coastal waters of the island of Hawai’i. Harmful Algae, 6(5), 658–669. https://doi.org/10.1016/j.hal.2007.01.001

[84] Parsons, M., Settlemier, C., & Ballauer, J. (2011). An examination of the epiphytic nature of Gambierdiscus toxicus, a dinoflagellate involved in ciguatera fish poisoning. Harmful Algae, 10(6), 598–605. https://doi.org/10.1016/j.hal.2011.04.011

[85] Paz, B., Vázquez, J., Riobó, P., & Franco, J. (2006). Study of the effect of temperature, irradiance and salinity on growth and yessotoxin production by the dinoflagellate Protoceratium reticulatum in culture by using a kinetic and factorial approach. Marine Environmental Research, 62(4), 286–300.

[86] https://doi.org/10.1016/j.marenvres.2006.04.066

[87] Pearce, I., Marshall, J., & Hallegraeff, G. (2001). No Title. In: Hallegraeff, G.M., Blackburn, S.I., Bolch, C.J., Lewis, R.J. (Eds.), Harmful Algal Blooms 2000. Intergovernmental Oceanographic Commission of UNESCO, Hobart, Tasmania, 54–57.

[88] Penna, A., Garcés, E., Vila, M., Giacobbe, M. G., Fraga, S., Lugliè, A., Lugliè, A., Bravo, I., Bertozzini, & E. Vernesi, C. (2005). Alexandrium catenella (Dinophyceae), a toxic ribotype expanding in the NW Mediterranean Sea. Marine Biology, 148(1), 13–23.

[89] https://doi.org/10.1007/s00227-005-0067-5

[90] Praptiwi, R. A. (2014). Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima. (Robert Gordon University).

[91] https://doi.org/10.1177/0266242610391936

[92] Rains, L. K., & Parsons, M. L. (2015). Gambierdiscus species exhibit different epiphytic behaviors toward a variety of macroalgal hosts. Harmful Algae, 49, 29–39.

[93] https://doi.org/10.1016/j.hal.2015.08.005

[94] Reguera, B., Alonso, R., Moreira, Á., & Silvia, M. (2011). Guía para el diseño y puesta en marcha de un plan de seguimiento de microalgas productoras de toxinas. Manuales y Guías COI de UNESCO y OIEA, Paris y Viena. Manuales y Guías de La COI, 59, 1–49.

[95] Stein, J. (1973). Handbook of Phycological Methods: Culture Methods and Growth Measurements (Cambridge).

[96] Tarazona-Janampa, U. (2019). Effect of associated bacteria on growth and toxigenicity in cultured isolates of the dinoflagellate Prorocentrum lima from Mexico Effect of associated bacteria on growth and toxigenicity in cultured isolates of the dinoflagellate Prorocentrum lima from Me (Universidad Veracruzana, Mexico).

[97] https://doi.org/htpps//:10.13140/RG.2.2.12826.90567

[98] Tarazona-Janampa, U., Cembella, A., Pelayo-Zárate, M., Pajares, S., Márquez-Valdelamar, L., Okolodkov, Y., Tebben, J., Krock, B., & Durán-Riveroll, L. (2020). Associated Bacteria and Their Effects on Growth and Toxigenicity of the Dinoflagellate Prorocentrum lima Species Complex From Epibenthic Substrates Along Mexican Coasts. Frontiers in Marine Science |, 7(569), 1–18.

[99] https://doi.org/10.3389/fmars.2020.00569

[100] Tawong, W., Nishimura, T., Sakanari, H., Sato, S., Yamaguchi, H., & Adachi, M. (2014). Distribution and molecular phylogeny of the dinoflagellate genus Ostreopsis in Thailand. Harmful Algae, 37, 160–171. https://doi.org/10.1016/j.hal.2014.06.003

[101] Tester, P. A., Kibler, S. R., Holland, W. C., Usup, G., Vandersea, M. W., Leaw, C. P., Mohammad-Noor, N., Faust, M., & Litaker, R. W. (2014). Sampling harmful benthic dinoflagellates: Comparison of artificial and natural substrate methods. Harmful Algae, 39, 8–25. https://doi.org/10.1016/j.hal.2014.06.009

[102] Torgensen, T., Miles, C., Rundberget, T., & Wilkins, A. (2008). New Esters of Okadaic Acid in Seawater and Blue Mussels (Mytilus edulis). J. Agric. Food Chem, 56, 9628–9635.

[103] Uchida, H., Watanabe, R., Matsushina, R., Uchida, N., Nagai, H., Kamio, M., Murata, M., Yasumoto, T., & Suzuki, T. (2014). A Convenient HPLC Method for Detection of Okadaic Acid Analogs as 9-Anthrylmethyl Esters with Automated Sample Cleanup by Column Switching. Journal of Aoac International, 97(2), 391–397. https://doi.org/10.5740/jaoacint.SGEUchida

[104] Vale, P., Veloso, V., & Amorim, A. (2009). Toxin composition of a Prorocentrum lima strain isolated from the Portuguese coast. Toxicon, 54(2), 145–152. https://doi.org/10.1016/j.toxicon.2009.03.026

[105] Vanucci, S., Guerrini, F., Milandri, A., & Pistocchi, R. (2010). Effects of different levels of N- and P-deficiency on cell yield , okadaic acid , DTX-1 , protein and carbohydrate dynamics in the benthic dinoflagellate Prorocentrum lima. Harmful Algae, 9(6), 590–599. https://doi.org/10.1016/j.hal.2010.04.009

[106] Varkitzi, I., Hatzianestis, I., Pyrgaki, C., Pagou, K., Granelí, E., Pavlidou, A., Montesanto, B., & Economou-Amilli, A. (2010). Unbalanced N:P ratios and nutrient stress controlling growth and toxin production of the harmful

[107] dinoflagellate Prorocentrum lima (Ehrenberg) Dodge. Harmful Algae, 9, 304–311. https://doi.org/10.1016/j.hal.2009.12.001

[108] Águila-Ramírez, R., Arenas-González, A., Hernández-Guerrero, C., González-Acosta, B., Borges-Souza, J., Véron, B., & Hellio, C. (2012). Antimicrobial and antifouling activities achieved by extracts of seaweeds from Gulf of California, Mexico. Hidrobiologica, 22(1), 8–15.

[109] Aligizaki, K., & Nikolaidis, G. (2006). The presence of the potentially toxic genera Ostreopsis and Coolia (Dinophyceae) in the North Aegean Sea, Greece. Harmful Algae, 5(6), 717–730

[110] https://doi.org/10.1016/j.hal.2006.02.005

[111] Aligizaki, K., & Nikolaidis, G. (2008). Morphological identification of two tropical dinoflagellates of the genera Gambierdiscus and Sinophysis in the Mediterranean Sea. Journal of Biological Research, 9, 75–82.

[112] Aligizaki, K., Nikolaidis, G., Katikou, P., Baxevanis, A., & Abatzopoulos, T. (2009). Potentially toxic epiphytic Prorocentrum (Dinophyceae) species in Greek coastal waters. Harmful Algae, 8(2), 299–311.https://doi.org/10.1016/j.hal.2008.07.002

[113] Aquino-Cruz, A., Purdie, D., & Morris, S. (2018). Effect of increasing sea water temperature on the growth and toxin production of the benthic dinoflagellate Prorocentrum lima. Hydrobiologia, 813(1), 103–122. https://doi.org/10.1007/s10750-018-3512-4

[114] Arbeláez, N., Mancera-Pineda, J., & Reguera, B. (2020). Structural variation of potentially toxic epiphytic dinoflagellates on Thalassia testudinum from two coastal systems of Colombian Caribbean. Harmful Algae, 92(January), 101738. https://doi.org/10.1016/j.hal.2019.101738

[115] Aumeerun, S., Soulange-Govinden, J., Driver, M., Rao, A., Ravishankar, G., & Neetoo, H. (2019). Macroalgae and Microalgae. In Handbook of Algal Technologies

[116] and Phytochemicals (p. 207).

[117] Berdalet, E., Fleming, L., Gowen, R., Davidson, K., Hess, P., Backer, L., Moore, S., Hoagland, P. & Enevoldsen, H. (2016). Marine harmful algal blooms, human health and wellbeing: challenges and opportunities in the 21st century. Journal of the Marine Biological Association of the United Kingdom, 96(1), 61–91. https://doi.org/https//: 10.1017/ S00253 15415001733

[118] Bomber, J., & Aikman, K. (1989). The Ciguatera Dinoflagellates. Biological Oceanography, 6, 291–311.

[119] Bomber, J., Guillard, R., & Nelson, W. (1988). Roles of temperature, salinity, and light in seasonality, growth, and toxicity of ciguatera-causing Gambierdiscus toxicus Adachi et Fukuyo (Dinophyceae). J. Exp. Mar. Biol. Ecol., 115, 53–65.

[120] Bomber, J., Rubio, M., & Norris, D. (1989). Epiphytism of dinoflagellates associated with the disease ciguatera: substrate specificity and nutrition. Phycologia, 28(3), 360–368.

[121] https://doi.org/10.2216/i0031-8884-28-3-360.1

[122] Bravo, I., Fernández, M. L., Ramilo, I., & Martínez, A. (2001). Toxin composition of the toxic dinoflagellate Prorocentrum lima isolated from different locations along the Galician coast (NW Spain). Toxicon, 39(10), 1537–1545. https://doi.org/10.1016/S0041-0101(01)00126-X

[123] Bravo, I., Rodríguez, F., Ramilo, I., & Afonso-Carrillo, J. (2020). Epibenthic Harmful Marine Dinoflagellates from Fuerteventura (Canary Islands), with Special Reference to the Ciguatoxin-Producing Gambierdiscus. J. Mar. Sci. Eng., 8, 0909.

[124] Carlson, R., Morey-Gaines, G., Tindall, D., & Dickey, R. (1984). Ecology of Toxic Dinoflagellates from the Caribbean Sea Effects of Macroalgal Extracts on Growth in Culture. Sea Food Toxins, 24, 271–

[125] https://doi.org/doi:10.1021/bk-1984-0262.ch024

[126] Catuto-Magallan, R. (2019). Composición y abundancia de dinoflagelados epibentónicos asociados a macroalgas en dos playas de la Provincia de Santa Elena. Universidad Estatal Península de Santa Elena.

[127] Chandia, P. (2020). Valor agregado a macroalgas chilenas de exportación: caracterización de ficocoloides, denominación de origen y diversificación comercial. Proyecto BBPP 18BPE-93853.

[128] Chinain, M., Germain, M., Deparis, X., Pauillac, S., & Legrand, A. (1999). Seasonal abundance and toxicity of the dinoflagellate Gambierdiscus spp. (Dinophyceae), the causative agent of ciguatera in Tahiti, French Polynesia. Marine Biology, 135, 259–267. https://doi.org/doi: 10.1007/s002270050623

[129] David, H., Laza-Martínez, A., Kromkamp, J. C., & Orive, E. (2018). Physiological response of Prorocentrum lima (Dinophyceae) to varying light intensities. FEMS Microbiology Ecology, 94(1), 1–12. https://doi.org/10.1093/femsec/fix166

[130] Faust, M. (1995). Observation of sand-dwelling toxic dinoflagellates (Dinophyceae) from widely differing sites, incluiding two new species. Journal Phycol., 42, 154–159.

[131] Faust, M. A. (1998). Mixotrophy in tropical benthic dinoflagellates. In: Reguera, B., Blanco, J. Fernandez, L., Wyatt, T. (Eds.) Harmful Algae. Xunta de Galicia and Intergovernmental Oceanographic Commission of UNESCO, Paris, Pp 390-393.

[132] Faust, M., & Gulledge, R. (2004). Identifying Harmful Marine Dinoflagellates. Journal of Applied Phycology, 16(1), 79. https://doi.org/10.1023/b:japh.0000019147.40273.1b

[133] Faust, M. A. (1991). Morphology of Ciguatera-causing Prorocentrum lima (Pyrrophyta) from widely differing sites. J. Phycol., 27, 642–648.

[134] Foden, J., Purdie, D., Morris, S., & Nascimento, S. (2005). Epiphytic abundance and toxicity of Prorocentrum lima populations in the Fleet Lagoon, UK. Harmful Algae, 4, 1063–1074.

[135] https://doi.org/https//:10.1016/j.hal.2005.03.004

[136] Fukuyo, Y. (1981). Taxonomical Study on Benthic Dinoflagellates Collected in Coral Reefs. Bulletin of the Japanese Society of Scientific Fisheries, 47(8), 967–978.

[137] GEOHAB. (2012). Global Ecology and Oceanography of Harmful Algal Blooms, GEOHAB Core Research Project: HABs in Benthic Systems. In A. Berdalet, E., Tester, P., Zingone (Ed.), Organization. IOC of UNESCO and SCOR, Paris and Newark.

[138] Gu, S., Xiao, S., Zheng, J., Li, H., Liu, J., & Yang, W. (2019). ABC Transporters in Prorocentrum lima and Their Expression Under Different Environmental Conditions Including Okadaic Acid Production. Marine Drugs, 17(259), 1–16.

[139] Guillard, R. R. L., & Hargraves, P. E. (1993). Stichochrysis immobilis is a diatom, not a chrysophyte. Phycologia, 32(3), 234–236. https://doi.org/10.2216/i0031-8884-32-3-234.1

[140] Hachani, M. A., Dhib, A., Fathalli, A., Ziadi, B., Turki, S., & Aleya, L. (2018). Harmful epiphytic dinoflagellate assemblages on macrophytes in the Gulf of Tunis. Harmful Algae, 77(June), 29–42.

[141] https://doi.org/10.1016/j.hal.2018.06.006

[142] Hales, S., Weinstein, P., & Woodward, A. (1999). Ciguatera (Fish Poisoning), El Niño, and Pacific Sea Surface Temperatures. Ecosystem Health, 5, 20–25.

[143] https://doi.org/doi: 10.1046/j.1526-0992. 1999. 0990 3.x

[144] Heredia-Tapia, A., Arredondo-Vega, B., Nuñez-Vázquez, E., Yasumoto, T., Yasuda, M., & Ochoa, J. (2002). Isolation of Prorocentrum lima (Syn. Exuviella lima) and diarrhetic shellfish poisoning (DSP) risk assessment in the Gulf of California, Mexico. Toxicon 4, 40, 1121–1127.

[145] Hou, D., Liang, J., Zou, C., Li, H., Liu, J., & Yang, W. (2015). MRP functional activity and character in the dinoflagellate Prorocentrum lima. Journal of Applied Phycology, 28, 1667–1676.

[146] https://doi.org/https//:10.1007/s10811-015-0679-1

[147] Hu, Tingmo, LeBlanc, P., Burton, I. W., Walter, J. A., McCarron, P., Melanson, J. E., Strangman, W., & Wright, J. L. C. (2017). Sulfated diesters of okadaic acid and DTX-1: Self-protective precursors of diarrhetic shellfish poisoning (DSP) toxins. Harmful Algae, 63, 85–93. https://doi.org/10.1016/j.hal.2017.01.012

[148] Hu, W., Xu, J., Sinkkonen, J., & Wu, J. (2010). Polyketides from Marine Dinoflagellates of the Genus Prorocentrum, Biosynthetic Origin and Bioactivity of Their Okadaic Acid Analogues. Mini-Reviews in Medicinal Chemistry, 10, 51–61.

[149] https://doi.org/10.2174/138955710791112541

[150] Irola-Sansores, E. D., Delgado-Pech, B., García-Mendoza, E., Núñez-Vázquez, E. J., Olivos-Ortiz, A., & Almazán-Becerril, A. (2018). Population dynamics of benthic-epiphytic dinoflagellates on two macroalgae from coral reef systems of the northern Mexican Caribbean. Frontiers in Marine Science, 5, 1–14.

[151] https://doi.org/10.3389/fmars.2018.00487

[152] Karafas, S., York, R., & Tomas, C. (2015). Morphological and genetic analysis of the Coolia monotis species complex with the introduction of two new species, Coolia santacroce sp. nov. and Coolia palmyrensis sp. nov. (Dinophyceae). Harmful Algae, 46, 18–33.

[153] https://doi.org/10.1016/j.hal.2015.05.002

[154] Kibler, S. R., Tester, P. A., Kunkel, K. E., Moore, S. K., & Litaker, R. W. (2015). Effects of ocean warming on growth and distribution of dinoflagellates associated with ciguatera fish poisoning in the Caribbean. Ecological Modelling, 316, 194–210.

[155] https://doi.org/10.1016/j.ecolmodel.2015.08.020

[156] Lartigue, J., Jester, E. L. E., Dickey, R. W., & Villareal, T. A. (2009). Nitrogen source effects on the growth and toxicity of two strains of the ciguatera-causing dinoflagellate Gambierdiscus toxicus. Harmful Algae, 8, 781–791. https://doi.org/10.1016/j.hal.2008.05.006

[157] Lassus, P., Chomerat, N., Hess, P., & Nezan, E. (2016). Microalgues toxiques et nuisibles de l’océan mondial. COI Manuels et Guides, 68 / Toxic and Harmful Microalgae of the World Ocean. IOC Manuals and Guides, 68.

[158] Laza-Martinez, A., Orive, E., & Miguel, I. (2011). Morphological and genetic characterization of benthic dinoflagellates of the genera Coolia, Ostreopsis and Prorocentrum from the south-eastern Bay of Biscay. European Journal of Phycology, 46(1), 45–65.

[159] https://doi.org/10.1080/09670262.2010.550387

[160] Lee, S., Hwang, B., Kim, H., Yih, W., & Jeong, E. (2015). A New Diol Ester Derivative of Dinophysistoxin-1 from Cultures of Prorocentrum lima Collected in South Korea. Bulletin of the Korean Chemical Society, 395–398. https://doi.org/10.1002/bkcs.10031

[161] LeGresley, M., & McDermott, G. (2010). Counting chamber methods for quantitative phytoplankton analysis - haemocytometer, Palmer-Maloney cell and Sedgewick-Rafter cell. In Microscopic and molecular methods for Quantitative phytoplankton analysis, 25–30.

[162] Levasseur, M., Thompson, P., & Harrison, P. (1993). Physiological acclimation of marine phytoplankton to different nitrogen sources. J. Phycol., 29, 587–595.

[163] Lewis, N., Wolny, J., Achenbach, J., Ellis, L., Pitula, J., Rafuse, C., Rosales, D. & McCarron, P. (2018). Identification, growth and toxicity assessment of Coolia meunier (Dinophyceae) from Nova Scotia, Canada. Harmful Algae, 75, 45–56.

[164] https://doi.org/10.1016/j.hal.2018.04.001

[165] Litaker, R. W., Vandersea, M. W., Faust, M. A., Kibler, S. R., Nau, A. W., Holland, W. C., Chinain, M., Holmes, M., & Tester, P. A. (2010). Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus. Toxicon, 56(5), 711–730.

[166] https://doi.org/10.1016/j.toxicon.2010.05.017

[167] Lobel, P., Anderson, D., & Durand-Clement, M. (1988). Assessment of Ciguatera Dinoflagellate Populations: Sample Variability and Algal Substrate Selection. The Biological Bulletin, 175(1), 94–101. https://doi.org/10.2307/1541896

[168] López-Rosales, L., Gallardo-Rodríguez, J. J., Sánchez-Mirón, A., Cerón-García, M. del C., Belarbi, E. H., García-Camacho, F., & Molina-Grima, E. (2013). Simultaneous effect of temperature and irradiance on growth and okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum. Toxins, 6(1), 229–253.

[169] https://doi.org/10.3390/toxins6010229

[170] Mangialajo, L., Ganzin, N., Accoroni, S., Asnaghi, V., Blanfuné, A., Cabrini, M., Chavanon, F., Chiantore, M., Cohu, S., Costa, E., Fornasaro, D., Grossel, H., Marco-Miralles, F., Masó, M., Reñé, A., Rossi, A., Sala, M., Thibaut, T., Totti, C., Vila, M., & Lemée, R. (2011). Trends in Ostreopsis proliferation along the Northern Mediterranean coasts. Toxicon, 57(3), 408–420.

[171] https://doi.org/10.1016/j.toxicon.2010.11.019

[172] Marr, J., Hu, T., Pleasance, S., Quilliam, M., & Wright, J. (1992). Detection of new 7-O-acyl derivatives of diarrhetic shellfish poisoning toxins by liquid chromatography-mass spectrometry. Toxicon, 30(12), 1621–1630.

[173] Matsuhiro, B., & Urzúa, C. (1990). Agars from Gracilaria chilensis (Gracilariales). Journal of Applied Phycology, 2(3), 273–279. https://doi.org/https//:10.1007/BF02179785

[174] McLachlan, J. L., Marr, J. C., Conlon?Keily, A., & Adamson, A. (1994). Effects of nitrogen concentration and cold temperature on DSP?toxin concentrations in the dinoflagellate Prorocentrum lima (prorocentrales, dinophyceae). Natural Toxins, 2(5), 263–270.

[175] https://doi.org/10.1002/nt.2620020504

[176] Moreira-González, A. R., Fernandes, L. F., Uchida, H., Uesugi, A., Suzuki, T., Chomérat, N., Bilien, G., & Mafra, L. L. (2018). Variations in morphology, growth, and toxicity among strains of the Prorocentrum lima species complex isolated from Cuba and Brazil. Journal of Applied Phycology, 31(1), 519–532.

[177] https://doi.org/10.1007/s10811-018-1587-y

[178] Morton, S., & Faust, M. (1997). Survey of Toxic Epiphytic Dinoflagellates from the Belizean Barrier Reef Ecosystem. Bulletin of Marine Science -Miami, 61(3), 899–906.

[179] Morton, S., Norris, D., & Bomber, J. (1992). Effect of temperature, salinity and light intensity on the growth and seasonality of toxic dinoflagellates associated with ciguatera. Journal of Experimental Marine Biology and Ecology, 157, 79–90.

[180] https://doi.org/10.1016/0022-0981(92)90076-M

[181] Murakami, Y., Oshima, Y., & Yasumoto, T. (1982). Identification of Okadaic Acid As a Toxic Component of a Marine Dinoflagellate Prorocentrum lima. Nippon Suisan Gakkaishi, 48(1), 69–72. https://doi.org/https//:10.2331/suisan.48.69

[182] Nagahama, Y., Murray, S., Tomaru, A., & Fukuyo, Y. (2011). Species boundaries in the toxic dinoflagellate Prorocentrum lima (Dinophyceae, Prorocentrales), based on morphological and phylogenetic characters. Journal of Phycology, 47(1), 178–189.

[183] https://doi.org/10.1111/j.1529-8817.2010.00939.x

[184] Nakahara, H., Sakami, T., Chinain, M., & Ishida, Y. (1996). The role of macroalgae in epiphytism of the toxic dinoflagellate Gambierdiscus toxicus (Dinophyceae). Phycological Research, 44(2), 113–117. https://doi.org/10.1111/j.1440-1835.1996.tb00385.x

[185] Nascimento, S. M., Purdie, D. A., & Morris, S. (2005). Morphology, toxin composition and pigment content of Prorocentrum lima strains isolated from a coastal lagoon in southern UK. Toxicon, 45(5), 633–649. https://doi.org/10.1016/j.toxicon.2004.12.023

[186] Nascimento, S. M., Salgueiro, F., Menezes, M., Oliveira, F. de A., Magalhães, V. C. P., De Paula, J. C., & Morris, S. (2016). Prorocentrum lima from the South Atlantic: Morphological, molecular and toxicological characterization. Harmful Algae, 57, 39–48.

[187] https://doi.org/10.1016/j.hal.2016.05.006

[188] Nishimura, T., Uchida, H., Noguchi, R., Oikawa, H., Suzuki, T., Funaki, H., hara, C., Hagino, K., Arimitsu, S., Tanii, Y., Abe, S., Hashimoto, K., Mimura, K., Tanaka, K., Yanagida., & I. Adachi, M. (2020). Abundance of the benthic dinoflagellate Prorocentrum and the diversity, distribution, and diarrhetic shellfish toxin production of Prorocentrum lima complex and P. caipirignum in Japan. Harmful Algae, 96, 101687. https://doi.org/10.1016/j.hal.2019.101687

[189] Okolodrov, Y., Merino-Virgilio, F., Aké-Castillo, J., Aguilar-Trujillo, A., Espinoza-Matías, S., & Herrera-Silveira, J. (2014). Seasonal changes in epiphytic dinoflallelate assemblages near the Northern coast ot the Yucatan peninsula, Gulf of Mexico. Acta Botanica Mexicana, 107, 121–151.

[190] Parsons, M., & Preskitt, L. (2007). A survey of epiphytic dinoflagellates from the coastal waters of the island of Hawai’i. Harmful Algae, 6(5), 658–669. https://doi.org/10.1016/j.hal.2007.01.001

[191] Parsons, M., Settlemier, C., & Ballauer, J. (2011). An examination of the epiphytic nature of Gambierdiscus toxicus, a dinoflagellate involved in ciguatera fish poisoning. Harmful Algae, 10(6), 598–605. https://doi.org/10.1016/j.hal.2011.04.011

[192] Paz, B., Vázquez, J., Riobó, P., & Franco, J. (2006). Study of the effect of temperature, irradiance and salinity on growth and yessotoxin production by the dinoflagellate Protoceratium reticulatum in culture by using a kinetic and factorial approach. Marine Environmental Research, 62(4), 286–300.

[193] https://doi.org/10.1016/j.marenvres.2006.04.066

[194] Pearce, I., Marshall, J., & Hallegraeff, G. (2001). No Title. In: Hallegraeff, G.M., Blackburn, S.I., Bolch, C.J., Lewis, R.J. (Eds.), Harmful Algal Blooms 2000. Intergovernmental Oceanographic Commission of UNESCO, Hobart, Tasmania, 54–57.

[195] Penna, A., Garcés, E., Vila, M., Giacobbe, M. G., Fraga, S., Lugliè, A., Lugliè, A., Bravo, I., Bertozzini, & E. Vernesi, C. (2005). Alexandrium catenella (Dinophyceae), a toxic ribotype expanding in the NW Mediterranean Sea. Marine Biology, 148(1), 13–23.

[196] https://doi.org/10.1007/s00227-005-0067-5

[197] Praptiwi, R. A. (2014). Optimisation of high value metabolite production from benthic marine dinoflagellate Prorocentrum lima. (Robert Gordon University).

[198] https://doi.org/10.1177/0266242610391936

[199] Rains, L. K., & Parsons, M. L. (2015). Gambierdiscus species exhibit different epiphytic behaviors toward a variety of macroalgal hosts. Harmful Algae, 49, 29–39.

[200] https://doi.org/10.1016/j.hal.2015.08.005

[201] Reguera, B., Alonso, R., Moreira, Á., & Silvia, M. (2011). Guía para el diseño y puesta en marcha de un plan de seguimiento de microalgas productoras de toxinas. Manuales y Guías COI de UNESCO y OIEA, Paris y Viena. Manuales y Guías de La COI, 59, 1–49.

[202] Stein, J. (1973). Handbook of Phycological Methods: Culture Methods and Growth Measurements (Cambridge).

[203] Tarazona-Janampa, U. (2019). Effect of associated bacteria on growth and toxigenicity in cultured isolates of the dinoflagellate Prorocentrum lima from Mexico Effect of associated bacteria on growth and toxigenicity in cultured isolates of the dinoflagellate Prorocentrum lima from Me (Universidad Veracruzana, Mexico).

[204] https://doi.org/htpps//:10.13140/RG.2.2.12826.90567

[205] Tarazona-Janampa, U., Cembella, A., Pelayo-Zárate, M., Pajares, S., Márquez-Valdelamar, L., Okolodkov, Y., Tebben, J., Krock, B., & Durán-Riveroll, L. (2020). Associated Bacteria and Their Effects on Growth and Toxigenicity of the Dinoflagellate Prorocentrum lima Species Complex From Epibenthic Substrates Along Mexican Coasts. Frontiers in Marine Science |, 7(569), 1–18.

[206] https://doi.org/10.3389/fmars.2020.00569

[207] Tawong, W., Nishimura, T., Sakanari, H., Sato, S., Yamaguchi, H., & Adachi, M. (2014). Distribution and molecular phylogeny of the dinoflagellate genus Ostreopsis in Thailand. Harmful Algae, 37, 160–171. https://doi.org/10.1016/j.hal.2014.06.003

[208] Tester, P. A., Kibler, S. R., Holland, W. C., Usup, G., Vandersea, M. W., Leaw, C. P., Mohammad-Noor, N., Faust, M., & Litaker, R. W. (2014). Sampling harmful benthic dinoflagellates: Comparison of artificial and natural substrate methods. Harmful Algae, 39, 8–25. https://doi.org/10.1016/j.hal.2014.06.009

[209] Torgensen, T., Miles, C., Rundberget, T., & Wilkins, A. (2008). New Esters of Okadaic Acid in Seawater and Blue Mussels (Mytilus edulis). J. Agric. Food Chem, 56, 9628–9635.

[210] Uchida, H., Watanabe, R., Matsushina, R., Uchida, N., Nagai, H., Kamio, M., Murata, M., Yasumoto, T., & Suzuki, T. (2014). A Convenient HPLC Method for Detection of Okadaic Acid Analogs as 9-Anthrylmethyl Esters with Automated Sample Cleanup by Column Switching. Journal of Aoac International, 97(2), 391–397. https://doi.org/10.5740/jaoacint.SGEUchida

[211] Vale, P., Veloso, V., & Amorim, A. (2009). Toxin composition of a Prorocentrum lima strain isolated from the Portuguese coast. Toxicon, 54(2), 145–152. https://doi.org/10.1016/j.toxicon.2009.03.026

[212] Vanucci, S., Guerrini, F., Milandri, A., & Pistocchi, R. (2010). Effects of different levels of N- and P-deficiency on cell yield , okadaic acid , DTX-1 , protein and carbohydrate dynamics in the benthic dinoflagellate Prorocentrum lima. Harmful Algae, 9(6), 590–599. https://doi.org/10.1016/j.hal.2010.04.009

[213] Varkitzi, I., Hatzianestis, I., Pyrgaki, C., Pagou, K., Granelí, E., Pavlidou, A., Montesanto, B., & Economou-Amilli, A. (2010). Unbalanced N:P ratios and nutrient stress controlling growth and toxin production of the harmful

[214] dinoflagellate Prorocentrum lima (Ehrenberg) Dodge. Harmful Algae, 9, 304–311. https://doi.org/10.1016/j.hal.2009.12.001

[215] Varkitzi, I., Pagou, K., Pyrgaki, C., & Hatzianestis, I. (2017). A Biomass Upscale System for the Marine Dinoflagellate Prorocentrum lima and the Production of Bioactive Lipophilic Toxins. International Journal of Applied Sciences and Biotechnology, 5(4), 479–485. https://doi.org/10.3126/ijasbt.v5i4.18561

[216] Wang, L., Wang, X., Wu, H., & Liu, R. (2014). Overview on biological activities and molecular characteristics of sulfated polysaccharides from marine green algae in recent years. In Marine Drugs (Vol. 12). https://doi.org/10.3390/md12094984

[217] Wang, S., Chen, J., Li, Z., Wang, Y., Fu, B., Han, X., & Zheng, L. (2015). Cultivation of the benthic microalga Prorocentrum lima for the production of diarrhetic shellfish poisoning toxins in a vertical flat photobioreactor. Bioresource Technology, 179, 243–248. https://doi.org/https//:10.1016/j.biortech.2014.12.019

[218] Wu, H., Chen, J., Peng, J., Zhong, Y., Guo, M., Tan, Z., Tan, Z., Zhai, Y., & Lu, S. (2020). Nontarget screening and toxicity evaluation of diol esters of okadaic acid and dinophysistoxins reveal intraspecies difference of Prorocentrum lima. Environmental Science & Technology, 1–40. https://doi.org/10.1021/acs.est.0c03691

[219] Yang, A., Lee, S., Du Yoo, Y., Seop Kim, H., Ju Jeong, E., & Rho, J. (2017). Limaol: A Polyketide from the Benthic Marine Dinoflagellate Prorocentrum lima. Journal of Natural Products, 80, 1688–1692. https://doi.org/10.1021/acs.jnatprod.7b00127

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