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In Panama, most of the mining explorations take place in areas of difficult access, which generally have very poor topographic and topographic support; To this is added the conditions of a tropical rainy climate, with abundant rainfall and exuberant vegetation. The lack of updating of the geological charts makes it necessary to look for other methods of reference and the application of new tools for updating the current maps. At the global level, technologies are introduced in the geological mapping production and supported by the use of tools provided by geomatics, such as satellite images, global positioning systems (GPS) and Geographic Information Systems (GIS) and the integration of aerial vehicles. unmanned (Drones). In this way, the general objective of this work was the application of the aforementioned geomatic tools in the geological cartography of Azuero. The result of the investigation generated several maps that present different geological units that allow to validate the use of this methodology in lithological and structural studies of the region. The study has the support of the National Secretariat of Science and Technology (SENACYT) project IDS11-019 and with funds from the IFHARU- SENACYT doctoral scholarship program.