Cardiovascular diseases are one of the main causes of mortality worldwide; It was traditionally seen that the population affected by these diseases were over 65 years, however we now observe that this health problem persists and worse still in the increasingly younger population, which has raised the question, what risk factors Are associated with the increase of cardiovascular diseases among patients aged 25 - 49 years in the Arnulfo Arias Hospital Complex Madrid, from 2013 to 2016. The aim of this study is to determine the risk factors that are associated with the increase of cardiovascular diseases in patients aged 15-49 in C.H.Dr.A.A.M., for which an analytical case-control study was carried out, since The data of the exposure to the risk factors from the year 2013 to June 2016 were collected. Data were collected from secondary sources using the medical history record, the chemistry laboratories and the nursing admission note. The cases are the patients graduated between the ages of 15 to 49 years who were hospitalized in the year 2013 to June 2016 whose diagnosis was a cardiovascular disease and the controls are patients between the ages of 15 to 49 years who have been hospitalized in The same period mentioned above whose diagnosis of discharge is any diagnosis of ICD other than cardiovascular disease. For the level of statistical significance was used chi square test and for the analysis of risk factors we used the Odds Ratio or relative inequality test to measure the strength of association and for this we constructed the tetrahedron tables, also established the limits of confidence LC = OR 1 + Z2 / VX2; The data were processed using the Epinfo 7 program.