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The objective of this research is to identify the challenges faced by businesses and enterprises in Changuinola, Bocas del Toro, analyzing the administrative alternatives and the use of ICT that have served as support to improve the situation of local companies during and after the COVID-19 pandemic. Applied research is mixed in nature, with a descriptive approach. To collect the information, a questionnaire was used, consisting of closed and open questions. This study was developed with small and medium-sized businesses in the district of Changuinola, province of Bocas del Toro, Panama, a northwestern region bordering Costa Rica, where 162 SMEs currently operate, of which, through a confidence level of 95 % and a margin of error of 5%, a sample of 114 companies to be studied was obtained. To guarantee the presence of small and medium-sized companies from all the townships of the Changuinola district, a stratified sample was carried out by conglomerate. The results highlight that the
85% of those surveyed affirmed yes, indicating that the incorporation of ICT has had a positive impact on the development of their commercial activities, on the other hand, 50% indicated that the pandemic had a negative impact on the development of their activities. Likewise, 30% of the participants expressed that the impact was moderate on the development of their activities.