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This study has been approached from sociolinguistics, specifically, the lexicon available in students of the Spanish major at the University of Panama. This work has had the objective: to determine the sociocultural variables that influence the lexical production of these students. In the analysis of the responses, the Dispolex program of the Pan-Hispanic Project created by López (1995) and directed by Professor Bartol (2006) was used. Such a program made it possible to measure in different lexical fields called centers of interest: animals, clothing and means of transportation, the percentage of appearance of the words, the cohesion index, etc. The sex and sociocultural variables were analyzed. The probabilistic sample was 30 students from the program: selected at random, 15 from the afternoon shift and 15 from the night shift. The results obtained showed clear sociocultural differences in the sample, in contrast to the sex variable. This evidence will allow us to address the problem of the lack of lexical availability in students in a didactic and timely manner.