The presence of bioactive compounds in plants and animals, and their use in the management of plagues and diseases, and in basic research are discussed. We concluded that this natural compounds, are more frequent in plants and in sessile animals, mainly marine invertebrates, as result of the immobility and the intensive competence. On the other hand, plants and marine invertebrates found in the tropics of the world have more biological compounds than their temperate counterparts. We discuss the causes of this richness of secondary metabolites in plants and marine invertebrates.
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