According to the information gathered by the author, and unpublished data, historical distribution and new records of the hog-nosed skunk (Conepatus semistriatus) for Panama are presented, and ita historic distribution is discussed. These records extend the known distribution of this species from western, provinces of Bocas del Toro and Chiriqui, to central Panama, near the Panama Canal Watershed. A new distribution map for this species is proposed, and unconfirmed records from the Azuero Peninsula and the western region of the Province of Panama are presented.