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This research evaluates the potential for rainwater harvesting and storage in buildings in Panama City, with the aim of proposing sustainable solutions to the growing demand for drinking water. Using a 1,245 m² zinc-roofed building as a case study, a technical analysis was performed to determine the amount of water that can be collected annually, considering an average rainfall of 2,200 mm and a runoff coefficient of 0.85, adequate for this type of surface. The results indicated that approximately 2,328 m³ of water can be collected annually, equivalent to more than 2.3 million liters. Based on these data, optimal reservoir sizes were proposed for different water autonomy scenarios: 15, 30, and 60 days, recommending capacities of 97,000, 194,000, and 388,000 liters, respectively. In addition, tables and graphs were included to visualize the relationship between frequency of use and required tank capacity. The findings demonstrate that rainwater harvesting is not only technically feasible but also strategic from an environmental and economic perspective, as it could reduce pressure on drinking water systems and lessen the effects of surface runoff in urban areas. This study supports the need to promote public policies and regulations that encourage the incorporation of these systems in the design of new construction and in the retrofitting of existing buildings.