The development of transversal skills, such as critical thinking, problem solving and collaboration, has become a central objective in contemporary education. This paper presents a detailed analysis of the curricular and didactic interventions implemented in various educational institutions in Córdoba, Colombia, which have proven to be successful in the formation of these competencies. Through a case study, the pedagogical strategies adopted, the curricular adjustments made and the teaching resources used to facilitate meaningful and applied learning are explored. The findings highlight how innovative educational practices, such as project-based learning, interdisciplinary approach and technology integration, have played a crucial role in achieving positive results. Furthermore, the implications of these interventions for curriculum design and teacher training are discussed, highlighting the importance of a holistic approach that considers the particularities of the local context.