Between October 2002 and April 2003 birds inventories were made in Cerro Canajagua, Los Santos province. The purpose of this work is to provide general information about the avifauna of this locality, its conservation status, and its relationship with the characteristics of the landscape. The methods included the use of ornithological netting and widespread searches in three types of habitats (open area, forest edge, and forest). The major birds in conservation were determined according to four instances (protected by Law, CITES, list of fauna about conservation importance, and North American Breeding Birds Survey, BBS). Records of 109 species were obtained, 93 residents and 18 migratory from the Northern Hemisphere. 33 species conservation importance of were identified, some of them considered for more than one instance. Among them, 25 are protected by Law, 25 are included in the appendices of CITES, five species are in the lists of important fauna, and five migratory species show significant declining of their population in the last decades. Despite the great destruction of the natural habitats of Cerro Canajagua, it is still useful for a great variety of birds to inhabit, which together with other values, it supports its status as protected area. Nevertheless, the pressures that threat to destroy the biodiversity of the area still persist, from which a great amount of wild species and persons of that region of Azuero depend.