Semi-terrestrial crabs play an important role in the ecology mangroves systems, as well as constituting an important economic resource for coastal communities. Despite this, little things are known about their biology and fishery in Panama and in general in the Eastern Tropical Pacific. Due the lack of information about the harvest, biometry and reproductive condition of Ucides occidentalis and Cardisoma crassum from the Montijo Gulf , Veraguas, Panama, an investigation was carried out in the Montijo Gulf, where the samples were collected monthly between November 2014 to September 2015, using different extraction methods. For each specimen, cephalothoracic length (LC), cephalothoracic width (AC), total weight (PT), also sex and reproductive condition were recorded. Ucides occidentalis average LC was 44.5 mm, the AC was 72.1 mm and PT was 126.2 g. The sex ratio was skewed towards males (5.2:1). Seven mature females, two brooding females, and another 29 spent females were recorded. For Cardisoma crassum the average LC was 44.0 mm, AC was 62.6 mm and the PT averaged 118.3 g. The sex ratio was (1.5:1). Four brooding females and another 117 spent females were recorded. Males of both species were larger and heavier than their female conspecifics. The results indicated that follow up to the Montijo crab festival is necessary given the potential impact that it can have on the populations of these crustacean species, as well as further deepen in the ecological and fishery studies on these species, both in the Gulf of Montijo as the rest of the Panamanian Pacific.