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A total of 15 gilts (150 ± 14.6 kg) were randomly assigned to three treatments: 1) AN: addition of 20 mg altrenogest (Virbagest, progesterone) to the diet for 18 days; 2) ANH: similar to AN plus 10.5 µg of GnRH and 500 IU of hCG 24 and 96 hours, respectively, after the last application of progesterone; and 3) PL: six intramuscular injections of 600 mg progesterone (Proluten) at 72-hour intervals plus 10.5 µg of GnRH and 500 IU hCG 48 and 120 hours, respectively, after the last progesterone injection. Two IATFs were performed, one at 26 hours and another at 40 hours after hCG application. Although no significant differences were evident in the pregnancy rate (p>0.05), the sows synchronized with AN had, numerically, a 20% higher pregnancy rate compared to the other treatments. A reduction in the onset of estrus was obtained in the synchronized sows with ANH and PL compared to those synchronized with AN (p<0.05). The PL treatment was $20.65 and $21.93 cheaper than the AN and ANH treatments, respectively. In conclusion, the application of the PL protocol had a similar pregnancy rate and onset of heat than the ANH group, as well as a lower application cost per sow.